Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | HTR4 | Q13639 | 3/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GAK | O14976 | 1/20 | 0.45 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28787322 | 0.88 | EPHX2 (0.53) | HTR4MCHR1 | |
| SCHEMBL28787352 | 0.84 | MAPKAPK2 (0.51) | POLBHTR4USP30 | |
| SCHEMBL13846093 | 0.84 | HTR4 (0.53) | HTR4MCHR1DRD2DRD4DRD3 | |
| SCHEMBL13845987 | 0.84 | HTR4 (0.53) | HTR4MCHR1DRD2DRD4DRD3 | |
| SCHEMBL12426778 | 0.83 | HTR4 (0.48) | HTR4MCHR1DRD2DRD4DRD3 | |
| SCHEMBL12426777 | 0.83 | HTR4 (0.48) | HTR4MCHR1DRD2DRD4DRD3 | |
| SCHEMBL29531655 | 0.82 | ALDH1A1 (0.64) | MCHR1SMN1; SMN2USP30 | |
| SCHEMBL3548018 | 0.82 | HTR4 (0.57) | HTR4MCHR1DRD4 | |
| SCHEMBL3936747 | 0.82 | HTR4 (0.57) | HTR4MCHR1DRD4 | |
| SCHEMBL1927002 | 0.81 | KMT2A (0.54) | HTR4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114478539-B | Novel DCLK1 inhibitor and preparation method and application thereof | 中国人民解放军海军军医大学 | 2024-02-02 | — | — | CN | disclosed |
| CN-114478539-A | Novel DCLK1 inhibitor and preparation method and application thereof | 中国人民解放军海军军医大学 | 2022-05-13 | — | — | CN | disclosed |