Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.51 |
| ▸ | BTK | Q06187 | 4/20 | 0.47 |
| ▸ | ITK | Q08881 | 1/20 | 0.44 |
| ▸ | JAK3 | P52333 | 5/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.44 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.43 |
| ▸ | CDK14 | O94921 | 1/20 | 0.43 |
| ▸ | CCNY | Q8ND76 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28787353 | 0.89 | HTR4 (0.46) | HTR4 | |
| SCHEMBL28787334 | 0.84 | POLB (0.52) | USP30HTR4POLB | |
| SCHEMBL13846093 | 0.83 | HTR4 (0.53) | USP30HTR4 | |
| SCHEMBL13845987 | 0.83 | HTR4 (0.53) | USP30HTR4 | |
| SCHEMBL12426778 | 0.82 | HTR4 (0.48) | USP30HTR4 | |
| SCHEMBL12426777 | 0.82 | HTR4 (0.48) | USP30HTR4 | |
| SCHEMBL29152337 | 0.81 | DRD2 (0.46) | USP30HTR4 | |
| SCHEMBL1927002 | 0.80 | KMT2A (0.54) | HTR4 | |
| SCHEMBL12825174 | 0.80 | KMT2A (0.57) | — | |
| SCHEMBL13846090 | 0.79 | HTR4 (0.54) | USP30HTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114478539-A | Novel DCLK1 inhibitor and preparation method and application thereof | 中国人民解放军海军军医大学 | 2022-05-13 | — | — | CN | disclosed |