Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | GPR183 | P32249 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28787352 | 0.89 | MAPKAPK2 (0.51) | HTR4 | |
| SCHEMBL13575483 | 0.86 | CRBN (0.53) | HTR4ALDH1A1TSHRMCHR1KMT2A | |
| SCHEMBL13846128 | 0.84 | ACHE (0.49) | HTR4ALDH1A1TSHRMCHR1KMT2A | |
| SCHEMBL738237 | 0.84 | HTR4 (0.53) | HTR4MCHR1KMT2AAURKAAURKB | |
| SCHEMBL28787322 | 0.83 | EPHX2 (0.53) | HTR4ALDH1A1TSHRMCHR1KMT2A | |
| SCHEMBL2546256 | 0.83 | MAPK14 (0.52) | HTR4ALDH1A1KMT2AMEN1 | |
| SCHEMBL13667133 | 0.83 | ALDH1A1 (0.45) | HTR4ALDH1A1TSHRMCHR1KMT2A | |
| SCHEMBL12894091 | 0.83 | KMT2A (0.60) | ALDH1A1TSHRMCHR1KMT2AMEN1 | |
| SCHEMBL28787314 | 0.83 | TEAD1 (0.56) | ALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL13575549 | 0.83 | KMT2A (0.46) | HTR4ALDH1A1TSHRMCHR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114478539-A | Novel DCLK1 inhibitor and preparation method and application thereof | 中国人民解放军海军军医大学 | 2022-05-13 | — | — | CN | disclosed |