Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.43 |
| ▸ | IDO1 | P14902 | 5/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28787440 | 0.81 | CRHR1 (0.40) | HDAC6SMN1; SMN2TSHR | |
| SCHEMBL27808373 | 0.81 | CRHR1 (0.40) | HDAC6SMN1; SMN2TSHR | |
| SCHEMBL27808326 | 0.79 | HDAC1 (0.49) | HDAC1HDAC6HRH3HTTSMN1; SMN2 | |
| SCHEMBL27808501 | 0.79 | HDAC1 (0.49) | HDAC1HDAC6HRH3HTTSMN1; SMN2 | |
| SCHEMBL27808277 | 0.77 | KHK (0.49) | HRH3CYP11B1CYP11B2MAPK1 | |
| SCHEMBL27786338 | 0.77 | GCG (0.44) | HRH3 | |
| SCHEMBL9302839 | 0.76 | HDAC1 (0.67) | HDAC1HDAC6HRH3IDO1CYP11B1 | |
| SCHEMBL8739201 | 0.76 | HDAC1 (0.61) | HDAC1HDAC6HRH3IDO1CYP11B1 | |
| Tert-Butyl Formate SCHEMBL27786473 | 0.75 | HDAC1 (0.53) | HDAC1HDAC6HRH3IDO1CYP11B1 | |
| SCHEMBL3725969 | 0.75 | HDAC1 (0.55) | HDAC1HDAC6HRH3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101778838-A | Azacyclylbenzamide derivatives as histamine-3 antagonists | WYETH CORP | 2010-07-14 | — | — | CN | disclosed |