Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCG | P01275 | 4/20 | 0.44 |
| ▸ | GCGR | P47871 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.35 |
| ▸ | HPGDS | O60760 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27808348 | 0.81 | GPR119 (0.40) | GCGR | |
| SCHEMBL27808321 | 0.81 | GPR119 (0.40) | GCGR | |
| SCHEMBL27808277 | 0.80 | KHK (0.49) | HPGDSHRH3DPP4 | |
| SCHEMBL28787442 | 0.77 | HDAC1 (0.52) | HRH3 | |
| SCHEMBL14000452 | 0.75 | GCG (0.50) | GCGGCGRHRH3PARP1 | |
| SCHEMBL28787440 | 0.75 | CRHR1 (0.40) | NPC1 | |
| SCHEMBL27808373 | 0.75 | CRHR1 (0.40) | NPC1 | |
| SCHEMBL14000815 | 0.74 | GCG (0.52) | GCGGCGRHPGDSPARP1NPC1 | |
| Tert-Butyl Formate SCHEMBL27808400 | 0.74 | GCG (0.46) | GCGGCGRHPGDSPARP1 | |
| SCHEMBL3723766 | 0.73 | HDAC4 (0.54) | GCGPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101778838-A | Azacyclylbenzamide derivatives as histamine-3 antagonists | WYETH CORP | 2010-07-14 | — | — | CN | disclosed |