Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 2/20 | 0.32 |
| ▸ | KCNE1 | P15382 | 5/20 | 0.31 |
| ▸ | KCNQ1 | P51787 | 5/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2878754 | 1.00 | ABCC9 (0.32) | ABCC9KCNE1KCNQ1CYP1A2CYP2C9 | |
| SCHEMBL9661045 | 0.81 | CYP1A2 (0.55) | CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7402368 | 0.77 | ABCC9 (0.32) | ABCC9 | |
| SCHEMBL2889227 | 0.77 | ABCC9 (0.30) | ABCC9 | |
| SCHEMBL9197844 | 0.76 | HTR1A (0.39) | ABCC9KCNE1KCNQ1CYP1A2CYP2C19 | |
| SCHEMBL9197856 | 0.76 | HTR1A (0.39) | ABCC9KCNE1KCNQ1CYP1A2CYP2C19 | |
| SCHEMBL9197846 | 0.76 | HTR1A (0.39) | ABCC9KCNE1KCNQ1CYP1A2CYP2C19 | |
| SCHEMBL9032549 | 0.75 | KCNE1 (0.56) | ABCC9KCNE1KCNQ1 | |
| SCHEMBL9530286 | 0.75 | KCNE1 (0.53) | ABCC9KCNE1KCNQ1KDM4E | |
| SCHEMBL9032544 | 0.75 | KCNE1 (0.56) | ABCC9KCNE1KCNQ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732929-B1 | TRICYCLIC BENZOPYRAN COMPOUND AS ANTI-ARRHYTHMIC AGENTS | NISSAN CHEMICAL IND LTD (JP) | 2010-10-20 | — | — | EP | disclosed |
| US-20100069374-A1 | Tricyclic benzopyrane compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-03-18 | — | — | US | disclosed |
| US-7652008-B2 | 2,2,7,9-tetramethyl-4-[(2-phenylethyl)amino]-3,4-dihydro-2H-pyrano[2,3-g]quinolin-3-ol; 3-hydroxy-2,2,9-trimethyl-4-[(2-phenylethyl)amino]-3,4-dihydro-2H-pyrano[2,3-g]quinolin-7-carbonitrile; have the prolongation effect on refractory period | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-01-26 | — | — | US | disclosed |
| US-20080004262-A1 | Tricyclic Benzopyrane Compound as Anti-Arrhythmic Agents | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2008-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069374-A1 | Tricyclic benzopyrane compound | CBR1, CBR3, CYP2C9 | ABCC9 10/4885KCNE1 115/4885KCNQ1 810/4885 |
| US-20080004262-A1 | Tricyclic Benzopyrane Compound as Anti-Arrhythmic Agents | CBR1, CBR3, SCN8A | ABCC9 20/4885KCNE1 71/4885KCNQ1 576/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.