SCHEMBL2879079

SCHEMBL2879079

C=CCCC(=O)OCC#N

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
LMNA P02545 1/20 0.36
TSHR P16473 1/20 0.34
ABCC4 O15439 1/20 0.32
MAPT P10636 1/20 0.32
FAAH O00519 1/20 0.31
MGLL Q99685 1/20 0.31
ZDHHC20 Q5W0Z9 1/20 0.30
ZDHHC2 Q9UIJ5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15083454 0.84 L3MBTL1 (0.36) ALDH1A1LMNATSHRMAPTZDHHC20
SCHEMBL9360783 0.80 ADRA2A (0.37) ALDH1A1TSHRMAPTZDHHC20ZDHHC2
SCHEMBL7003693 0.79 ALDH1A1 (0.34) ALDH1A1LMNATSHRMAPT
SCHEMBL15083614 0.79
SCHEMBL15083603 0.79 CA12 (0.35) ALDH1A1LMNA
SCHEMBL5439764 0.78 ALDH1A1 (0.43) ALDH1A1LMNATSHRABCC4MAPT
SCHEMBL5712605 0.77
SCHEMBL11330333 0.76 ALDH1A1 (0.42) ALDH1A1LMNATSHRABCC4MAPT
SCHEMBL734227 0.76 ALDH1A1 (0.38) ALDH1A1ZDHHC20ZDHHC2
SCHEMBL3316103 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12415835-B2 Peptide-compound cyclization method CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-09-16 US disclosed
US-20240166689-A1 PEPTIDE-COMPOUND CYCLIZATION METHOD CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2024-05-23 US disclosed
US-11891457-B2 Peptide-compound cyclization method CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2024-02-06 US disclosed
EP-3974563-A1 CYCLIC PEPTIDES Chugai Seiyaku Kabushiki Kaisha (JP) 2022-03-30 EP disclosed
EP-2813512-B1 PEPTIDE-COMPOUND CYCLIZATION METHOD CHUGAI PHARMACEUTICAL CO LTD (JP) 2021-03-31 EP disclosed
US-20210061860-A1 PEPTIDE-COMPOUND CYCLIZATION METHOD CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2021-03-04 US disclosed
US-20170200973-A1 ELECTROLYTIC SOLUTION, SECONDARY BATTERY, BATTERY PACK, ELECTRIC VEHICLE, ELECTRIC POWER STORAGE SYSTEM, ELECTRIC POWER TOOL, AND ELECTRONIC APPARATUS TOHOKU MURATA MANUFACTURING CO., LTD. (JP) 2017-07-13 US disclosed
US-9608289-B2 Electrolytic solution, secondary battery, battery pack, electric vehicle, electric power storage system, electric power tool, and electronic apparatus SONY CORPORATION (JP) 2017-03-28 US disclosed
US-20160311858-A1 PEPTIDE-COMPOUND CYCLIZATION METHOD CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2016-10-27 US disclosed
US-9409952-B2 Peptide-compound cyclization method CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2016-08-09 US disclosed
US-20150080549-A1 PEPTIDE-COMPOUND CYCLIZATION METHOD CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2015-03-19 US disclosed
US-20150080549-A1 PEPTIDE-COMPOUND CYCLIZATION METHOD CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2015-03-19 US disclosed
US-20150080549-A1 PEPTIDE-COMPOUND CYCLIZATION METHOD CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2015-03-19 US disclosed
EP-2813512-A1 PEPTIDE-COMPOUND CYCLIZATION METHOD Chugai Seiyaku Kabushiki Kaisha (JP) 2014-12-17 EP disclosed
EP-2813512-A1 PEPTIDE-COMPOUND CYCLIZATION METHOD Chugai Seiyaku Kabushiki Kaisha (JP) 2014-12-17 EP disclosed
WO-2013100132-A1 PEPTIDE-COMPOUND CYCLIZATION METHOD 中外製薬株式会社 (JP) 2013-07-04 WO disclosed
US-7824899-B2 Preparation of enantiomerically enriched amines and amides by enzymatic resolution using a sulfonylacetic acid ester as acyl donor EVONIK DEGUSSA GMBH (DE) 2010-11-02 US disclosed
EP-1870475-B1 Process for the preparation of optically active amines and amides employing a hydrolase and sulfonyl acetic acid ester as the acyl donor EVONIK DEGUSSA GMBH (DE) 2008-12-10 EP disclosed
US-20070298471-A1 PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY ENRICHED AMINES AND AMIDES BY ENZYMATIC RESOLUTION DEGUSSA GMBH (DE) 2007-12-27 US disclosed
EP-1870475-A1 Process for the preparation of optically active amines and amides employing a hydrolase and sulfonyl acetic acid ester as the acyl donor Evonik Degussa GmbH (DE) 2007-12-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11891457-B2 Peptide-compound cyclization method VIP, NGLY1, GLP1R ALDH1A1 4857/4885LMNA 2193/4885TSHR 1056/4885
US-20210061860-A1 PEPTIDE-COMPOUND CYCLIZATION METHOD VIP, NGLY1, GLP1R ALDH1A1 4857/4885LMNA 2193/4885TSHR 1056/4885
US-20240166689-A1 PEPTIDE-COMPOUND CYCLIZATION METHOD VIP, NGLY1, GLP1R ALDH1A1 4857/4885LMNA 2193/4885TSHR 1056/4885
US-20160311858-A1 PEPTIDE-COMPOUND CYCLIZATION METHOD VIP, NGLY1, GLP1R ALDH1A1 4857/4885LMNA 2193/4885TSHR 1056/4885
US-20150080549-A1 PEPTIDE-COMPOUND CYCLIZATION METHOD VIP, NGLY1, GLP1R ALDH1A1 4857/4885LMNA 2193/4885TSHR 1056/4885
US-12415835-B2 Peptide-compound cyclization method VIP, NGLY1, GLP1R ALDH1A1 4857/4885LMNA 2193/4885TSHR 1056/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.