Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 5/20 | 0.42 |
| ▸ | HTR2A | P28223 | 3/20 | 0.42 |
| ▸ | HTR2B | P41595 | 3/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30503894 | 0.95 | LMNA (0.55) | ALDH1A1LMNAMAPTSMN1; SMN2SLC6A4 | |
| SCHEMBL30171037 | 0.77 | ATM (0.54) | ALDH1A1LMNAMAPTSLC6A4KDM4E | |
| SCHEMBL4212837 | 0.77 | ATM (0.54) | ALDH1A1LMNAMAPTSLC6A4KDM4E | |
| SCHEMBL7328589 | 0.76 | HTR1A (0.43) | SLC6A4HTR1A | |
| SCHEMBL14921847 | 0.75 | OPRM1 (0.55) | ALDH1A1LMNAMAPTSMN1; SMN2SLC6A4 | |
| SCHEMBL15602070 | 0.74 | ALDH1A1 (0.50) | ALDH1A1LMNAMAPTSLC6A4KDM4E | |
| SCHEMBL21047648 | 0.71 | SLC6A4 (0.43) | ALDH1A1LMNAMAPTSMN1; SMN2SLC6A4 | |
| SCHEMBL1969237 | 0.70 | HTR2A (0.68) | ALDH1A1LMNAMAPTSMN1; SMN2SLC6A4 | |
| SCHEMBL21921279 | 0.70 | ATM (0.48) | ALDH1A1LMNAMAPTKDM4EMEN1 | |
| SCHEMBL4982358 | 0.69 | MEN1 (0.54) | ALDH1A1LMNAMAPTSLC6A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102015682-A | 3, 4-substituted piperidine derivatives as renin inhibitors | MERCK FROSST CANADA LTD | 2011-04-13 | — | — | CN | disclosed |