Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | MMP3 | P08254 | 1/20 | 0.52 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.52 |
| ▸ | ABL1 | P00519 | 1/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.52 |
| ▸ | BCR | P11274 | 1/20 | 0.52 |
| ▸ | USP7 | Q93009 | 2/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27947405 | 1.00 | ALOX5 (0.53) | ALOX5MMP3BCL2L1ABL1ABCB1 | |
| SCHEMBL29141132 | 0.90 | HSD17B10 (0.56) | ABL1ABCB1BCRUSP7ESR2 | |
| SCHEMBL9505452 | 0.90 | HSD17B10 (0.56) | ABL1ABCB1BCRUSP7ESR2 | |
| SCHEMBL650894 | 0.88 | CYP3A4 (0.61) | CYP3A4HSD17B10TAAR1TDP1MEN1 | |
| SCHEMBL21582646 | 0.88 | HSD17B10 (0.61) | CYP3A4HSD17B10TAAR1TDP1MEN1 | |
| SCHEMBL25301803 | 0.88 | HSD17B10 (0.61) | CYP3A4HSD17B10TAAR1TDP1MEN1 | |
| SCHEMBL29658028 | 0.88 | HSD17B10 (0.61) | CYP3A4HSD17B10TAAR1TDP1MEN1 | |
| SCHEMBL29372308 | 0.88 | CYP3A4 (0.61) | CYP3A4HSD17B10TAAR1TDP1MEN1 | |
| SCHEMBL116465 | 0.88 | CYP3A4 (0.61) | CYP3A4HSD17B10TAAR1TDP1MEN1 | |
| SCHEMBL29830590 | 0.88 | HSD17B10 (0.61) | CYP3A4HSD17B10TAAR1TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102276484-A | Method for preparing 2-phenyl-4,4'-diamido diphenyl ether | — | 2011-12-14 | — | — | CN | claimed |
| CN-102276484-B | Method for preparing 2-phenyl-4,4'-diamido diphenyl ether | CHANGZHOU SUNLIGHT PHARM CO LTD | 2013-12-18 | — | — | CN | disclosed |
| CN-102276484-A | Method for preparing 2-phenyl-4,4'-diamido diphenyl ether | — | 2011-12-14 | — | — | CN | disclosed |
| CN-102276484-A | Method for preparing 2-phenyl-4,4'-diamido diphenyl ether | — | 2011-12-14 | — | — | CN | disclosed |