Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | THRB | P10828 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CA3 | P07451 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | CA6 | P23280 | 1/20 | 0.56 |
| ▸ | CASP1 | P29466 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.56 |
| ▸ | APP | P05067 | 3/20 | 0.50 |
| ▸ | USP7 | Q93009 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 3/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | BCR | P11274 | 1/20 | 0.47 |
| ▸ | CLK1 | P49759 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29141132 | 1.00 | HSD17B10 (0.56) | HSD17B10THRBALDH1A1CYP3A4CA3 | |
| SCHEMBL28793603 | 0.90 | ALOX5 (0.53) | HSD17B10THRBALDH1A1CYP3A4CA3 | |
| SCHEMBL27947405 | 0.90 | ALOX5 (0.53) | HSD17B10THRBALDH1A1CYP3A4CA3 | |
| SCHEMBL30880329 | 0.89 | ALDH1A1 (0.53) | HSD17B10ALDH1A1CYP3A4APPTP53 | |
| SCHEMBL14110641 | 0.89 | ALDH1A1 (0.53) | HSD17B10ALDH1A1CYP3A4APPTP53 | |
| SCHEMBL5685027 | 0.84 | CASP1 (0.52) | HSD17B10THRBALDH1A1CYP3A4CA3 | |
| SCHEMBL28349056 | 0.84 | ALDH1A1 (0.53) | HSD17B10ALDH1A1CYP3A4APPTP53 | |
| SCHEMBL2957667 | 0.83 | HSD17B1 (0.50) | ALDH1A1CYP3A4CA14ESR1ESR2 | |
| SCHEMBL692017 | 0.83 | USP7 (0.50) | HSD17B10THRBALDH1A1CYP3A4CA3 | |
| SCHEMBL2477753 | 0.83 | USP7 (0.50) | HSD17B10THRBALDH1A1CYP3A4CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0295126-B1 | ARYLAMINE-CONTAINING POLYHYDROXY ETHER RESINS | XEROX CORPORATION (US) | 1993-08-04 | — | — | EP | disclosed |
| US-4818650-A | Arylamine containing polyhydroxy ether resins and system utilizing arylamine containing polyhydroxyl ether resins | XEROX CORPORATION (US) | 1989-04-04 | — | — | US | disclosed |