Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28795264 | 0.96 | CNR1 (0.45) | MAPTALDH1A1LMNACNR1DRD2 | |
| SCHEMBL28795397 | 0.88 | ALDH1A1 (0.45) | MAPTALDH1A1LMNASMN1; SMN2GPR174 | |
| SCHEMBL28795429 | 0.86 | SMN1; SMN2 (0.48) | MAPTALDH1A1LMNASMN1; SMN2GPR174 | |
| SCHEMBL28795474 | 0.84 | ALDH1A1 (0.44) | MAPTALDH1A1LMNACNR1SMN1; SMN2 | |
| SCHEMBL31458457 | 0.84 | ALDH1A1 (0.44) | MAPTALDH1A1LMNACNR1SMN1; SMN2 | |
| SCHEMBL29803165 | 0.83 | ALDH1A1 (0.40) | MAPTALDH1A1LMNAGPR174L3MBTL1 | |
| SCHEMBL28795428 | 0.82 | GPR119 (0.44) | MAPTALDH1A1LMNASMN1; SMN2GPR174 | |
| SCHEMBL28795145 | 0.82 | MAPT (0.44) | MAPTALDH1A1LMNASMN1; SMN2GPR174 | |
| SCHEMBL28795232 | 0.82 | SMN1; SMN2 (0.41) | MAPTALDH1A1LMNASMN1; SMN2GPR174 | |
| SCHEMBL28795359 | 0.82 | SMN1; SMN2 (0.43) | MAPTALDH1A1LMNASMN1; SMN2GPR174 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114805303-A | Molecule with double functions of degrading EGFR (epidermal growth factor receptor), composition and pharmaceutical application thereof | 海思科医药集团股份有限公司 | 2022-07-29 | — | — | CN | disclosed |