Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GPR174 | Q9BXC1 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28795474 | 0.96 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2HTTGAAMAPT | |
| SCHEMBL31458457 | 0.96 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2HTTGAAMAPT | |
| SCHEMBL28795428 | 0.94 | GPR119 (0.44) | ALDH1A1SMN1; SMN2HTTMAPTLMNA | |
| SCHEMBL28795232 | 0.93 | SMN1; SMN2 (0.41) | ALDH1A1SMN1; SMN2HTTGAAMAPT | |
| SCHEMBL28795359 | 0.93 | SMN1; SMN2 (0.43) | ALDH1A1SMN1; SMN2HTTGAAMAPT | |
| SCHEMBL28795257 | 0.92 | GPR119 (0.40) | ALDH1A1SMN1; SMN2HTTGAAMAPT | |
| SCHEMBL31700584 | 0.91 | GPR174 (0.49) | ALDH1A1SMN1; SMN2GAAMAPTLMNA | |
| SCHEMBL28795396 | 0.90 | GPR119 (0.39) | ALDH1A1SMN1; SMN2HTTGAAMAPT | |
| SCHEMBL29059659 | 0.89 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2HTTGAAMAPT | |
| SCHEMBL28795438 | 0.88 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2HTTGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114805303-A | Molecule with double functions of degrading EGFR (epidermal growth factor receptor), composition and pharmaceutical application thereof | 海思科医药集团股份有限公司 | 2022-07-29 | — | — | CN | disclosed |