Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PRKDC | P78527 | 1/20 | 0.37 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | GNRHR | P30968 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28795257 | 0.94 | GPR119 (0.40) | GPR119POLBBACE1ALDH1A1SMN1; SMN2 | |
| SCHEMBL28795397 | 0.90 | ALDH1A1 (0.45) | GPR119POLBBACE1ALDH1A1SMN1; SMN2 | |
| SCHEMBL31458457 | 0.88 | ALDH1A1 (0.44) | GPR119POLBALDH1A1SMN1; SMN2HTT | |
| SCHEMBL28795474 | 0.88 | ALDH1A1 (0.44) | GPR119POLBALDH1A1SMN1; SMN2HTT | |
| SCHEMBL28795428 | 0.87 | GPR119 (0.44) | GPR119POLBALDH1A1SMN1; SMN2HTT | |
| SCHEMBL28795291 | 0.87 | ACACB (0.42) | ALDH1A1SMN1; SMN2HTTMAPTLMNA | |
| SCHEMBL31498867 | 0.86 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2HTTMAPTLMNA | |
| SCHEMBL28795237 | 0.86 | ALDH1A1 (0.43) | GPR119ALDH1A1SMN1; SMN2HTTMAPT | |
| SCHEMBL28795232 | 0.85 | SMN1; SMN2 (0.41) | GPR119POLBBACE1ALDH1A1SMN1; SMN2 | |
| SCHEMBL28795359 | 0.85 | SMN1; SMN2 (0.43) | GPR119POLBBACE1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114805303-A | Molecule with double functions of degrading EGFR (epidermal growth factor receptor), composition and pharmaceutical application thereof | 海思科医药集团股份有限公司 | 2022-07-29 | — | — | CN | disclosed |