SCHEMBL28795709

SCHEMBL28795709

N#COc1ccccc1OP

nearest known ligand 0.31

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA4 P22748 1/20 0.31
CA7 P43166 1/20 0.31
CA9 Q16790 1/20 0.31
CA14 Q9ULX7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL159732 0.87 CA1 (0.38) CA12CA1CA2CA4CA7
SCHEMBL30159634 0.87 CA1 (0.38) CA12CA1CA2CA4CA7
Ethylene SCHEMBL27752633 0.82 CA12 (0.35) CA12CA1CA2CA4CA7
SCHEMBL1324603 0.80 AR (0.38) CA12CA1CA2CA4CA7
SCHEMBL1465660 0.79 CA1 (0.44) CA12CA1CA2CA4CA7
SCHEMBL2405150 0.76 CA1 (0.62) CA12CA1CA2CA4CA7
SCHEMBL1305477 0.75 PIM1 (0.34) CA12CA1CA2CA4CA7
SCHEMBL22522695 0.74 MAP4K4 (0.35)
SCHEMBL3994528 0.74 ALDH1A1 (0.52)
SCHEMBL1324477 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114835752-A Phosphoryloxybenzonitrile compound and preparation method and application thereof 广东工业大学 2022-08-02 CN disclosed