Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL583005 | 0.70 | SIGMAR1 (0.37) | HDAC3 | |
| SCHEMBL20985812 | 0.70 | KCNH2 (0.41) | — | |
| SCHEMBL29809465 | 0.70 | BRD4 (0.37) | — | |
| SCHEMBL15558497 | 0.70 | TRPA1 (0.33) | — | |
| SCHEMBL4809969 | 0.67 | HSD17B3 (0.43) | — | |
| SCHEMBL20985797 | 0.67 | MAPT (0.31) | — | |
| SCHEMBL20985828 | 0.67 | L3MBTL1 (0.31) | — | |
| SCHEMBL20985751 | 0.67 | RAB9A (0.32) | — | |
| SCHEMBL20985766 | 0.67 | CBLB (0.31) | — | |
| SCHEMBL20985776 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102245593-A | Isoquinolinone derivatives | ASTRAZENECA AB | 2011-11-16 | — | — | CN | disclosed |