SCHEMBL28797245

SCHEMBL28797245

C[SiH](C)C1(CCCc2ccccc2)CCCCO1

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.35
SIGMAR1 Q99720 1/20 0.35
OPRM1 P35372 2/20 0.35
OPRL1 P41146 2/20 0.35
OPRD1 P41143 1/20 0.35
OPRK1 P41145 1/20 0.35
KDM4E B2RXH2 1/20 0.34
ALDH1A1 P00352 2/20 0.33
LMNA P02545 1/20 0.33
SLC18A3 Q16572 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5486438 0.82 MAOA (0.38) OPRM1OPRL1OPRK1
Methane SCHEMBL14661843 0.81 MAOA (0.37) OPRM1OPRL1OPRK1
SCHEMBL29185348 0.76
SCHEMBL3797389 0.75
SCHEMBL338864 0.75 SIGMAR1 (0.37) POLBSIGMAR1OPRM1OPRL1OPRD1
SCHEMBL27586838 0.74 ALDH1A1 (0.35) POLBSIGMAR1OPRM1OPRL1OPRD1
SCHEMBL7155933 0.73 CYP4F2 (0.30)
SCHEMBL7134159 0.73
SCHEMBL21003278 0.73
SCHEMBL28939437 0.73 SCN2A (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114845695-B External skin preparation composition 花王株式会社 2024-12-24 CN disclosed
CN-114845696-B External skin preparation composition 花王株式会社 2024-08-20 CN disclosed
CN-112512497-B Method for improving wrinkles of skin 花王株式会社 2023-12-22 CN disclosed
CN-116583257-A Compositions comprising (bio) -alkanediols 西姆莱斯股份公司 2023-08-11 CN disclosed
CN-114901248-A Composition for conditioning keratin fibers 莱雅公司 2022-08-12 CN disclosed
CN-114828816-A Composition for conditioning keratin fibers 莱雅公司 2022-07-29 CN disclosed