SCHEMBL338864

SCHEMBL338864

[SiH3]C1(CCCc2ccccc2)CCCCO1

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 5/20 0.37
POLB P06746 1/20 0.37
OPRM1 P35372 1/20 0.37
OPRD1 P41143 1/20 0.37
OPRK1 P41145 1/20 0.37
OPRL1 P41146 1/20 0.37
MAOA P21397 1/20 0.34
TAAR1 Q96RJ0 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16243044 0.95 OPRM1 (0.37) SIGMAR1POLBOPRM1OPRL1MAOA
SCHEMBL477537 0.90 KDM1A (0.35) OPRM1OPRL1MAOA
SCHEMBL28548973 0.87 CYP3A4 (0.30)
SCHEMBL27907645 0.85 MEN1 (0.37) SIGMAR1OPRM1TAAR1
SCHEMBL28605731 0.84
SCHEMBL60702 0.80 MAOA (0.41) SIGMAR1OPRM1OPRK1OPRL1MAOA
SCHEMBL27723526 0.80 MPO (0.38) OPRM1OPRK1TAAR1
SCHEMBL1464180 0.79 EPHX1 (0.40) SIGMAR1MAOATAAR1
SCHEMBL27668036 0.79 MAOA (0.40) SIGMAR1OPRM1OPRK1OPRL1MAOA
SCHEMBL28442078 0.78 CA2 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114276497-B Paraffin-modified styrene-acrylate-siloxane core-shell phase-change emulsion and preparation method and application thereof 青岛理工大学 2023-02-24 CN claimed
CN-114195945-B Styrene-acrylate-siloxane composite core-shell emulsion and preparation method and application thereof 青岛理工大学 2022-12-16 CN claimed
CN-114276497-A Paraffin-modified styrene-acrylate-siloxane core-shell phase-change emulsion and preparation method and application thereof 青岛理工大学 2022-04-05 CN claimed
CN-114195945-A Styrene-acrylate-siloxane composite core-shell emulsion and preparation method and application thereof 青岛理工大学 2022-03-18 CN claimed
US-4613640-A HYDROCARBON POLYMER, MINERAL OIL, POLYSILOXANES, MEDICAL EQUIPMENT MEDICAL RESEARCH ASSOCIATES, LTD. #2 (US) 1986-09-23 US claimed
CN-118994658-A High-residual-strength glass fiber reinforced resin composite material and preparation method thereof 中国石油化工股份有限公司 2024-11-22 CN disclosed
CN-116023833-B Preparation method of styrene-acrylic-siloxane interpenetrating polymer network composite emulsion 青岛理工大学 2023-11-24 CN disclosed
CN-116023833-A Preparation method of styrene-acrylic-siloxane interpenetrating polymer network composite emulsion 青岛理工大学 2023-04-28 CN disclosed
CN-114195945-B Styrene-acrylate-siloxane composite core-shell emulsion and preparation method and application thereof 青岛理工大学 2022-12-16 CN disclosed
CN-114195945-A Styrene-acrylate-siloxane composite core-shell emulsion and preparation method and application thereof 青岛理工大学 2022-03-18 CN disclosed
US-8119757-B2 Polysiloxane and urethane modified water-reducible alkyd resins CYTEC SURFACE SPECIALTIES AUSTRIA GMBH (AT) 2012-02-21 US disclosed
US-8097602-B1 Method of treating body insect infestation HOST PHARMACEUTICALS, LLC (US) 2012-01-17 US disclosed
CN-101792585-A Flame-retardant polycarbonate composition and preparation method thereof PANYU FANYU PLASTIC IND CO LTD 2010-08-04 CN disclosed
US-20100174035-A1 POLYSILOXANE AND URETHANE MODIFIED WATER-REDUCIBLE ALKYD RESINS CYTEC SURFACE SPECIALITIES AUSTRIA GMBH (AT) 2010-07-08 US disclosed
EP-2155801-A1 POLYSILOXANE AND URETHANE MODIFIED WATER-REDUCIBLE ALKYD RESINS Cytec Surface Specialties Austria GmbH (AT) 2010-02-24 EP disclosed
WO-2008148716-A1 POLYSILOXANE AND URETHANE MODIFIED WATER-REDUCIBLE ALKYD RESINS CYTEC SURFACE SPECIALTIES AUSTRIA GMBH (AT) 2008-12-11 WO disclosed
EP-2000491-A1 Polysiloxane and urethane modified water-reducible alkyd resins Cytec Surface Specialties Austria GmbH (AT) 2008-12-10 EP disclosed
EP-1002825-A2 Non-aqueous silicone emulsions GENERAL ELECTRIC COMPANY (US) 2000-05-24 EP disclosed
US-6060546-A COMPRISING A CROSSLINKED SILICONE ELASTOMER AND A LOW MOLECULAR WEIGHT SILICONE FLUID AND AN ORGANIC PHASE HAVING <50 PARTS BY WEIGHT WATER; PERSONAL CARE; DERMATOLOGY; COSMETICS; SKIN CREAM; ANTIPERSPIRANTS GENERAL ELECTRIC COMPANY (US) 2000-05-09 US disclosed
WO-1998055431-A1 PROCESS FOR THE CONVERSION OF HYDROCARBONS PHILLIPS PETROLEUM COMPANY (US) 1998-12-10 WO disclosed