SCHEMBL28797265

SCHEMBL28797265

CCCc1c(O)ccc(Br)c1CCC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.41
CNR2 P34972 1/20 0.41
KDM4E B2RXH2 3/20 0.35
ALDH1A1 P00352 3/20 0.35
HPGD P15428 2/20 0.35
GAA P10253 1/20 0.35
PRKCI P41743 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
DRD2 P14416 1/20 0.35
TSHR P16473 1/20 0.35
NFKB1 P19838 1/20 0.35
DRD1 P21728 1/20 0.35
DRD4 P21917 1/20 0.35
DRD5 P21918 1/20 0.35
ADRA1D P25100 1/20 0.35
ADRA1A P35348 1/20 0.35
ADRA1B P35368 1/20 0.35
DRD3 P35462 1/20 0.35
HIF1A Q16665 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1798100 0.90 CNR1 (0.37) CNR1CNR2KDM4EALDH1A1HPGD
SCHEMBL30027246 0.86 CNR1 (0.50) CNR1CNR2KDM4EALDH1A1HPGD
SCHEMBL1760417 0.86 CNR1 (0.50) CNR1CNR2KDM4EALDH1A1HPGD
SCHEMBL6232640 0.85 CNR1 (0.39) CNR1CNR2KDM4EALDH1A1HPGD
SCHEMBL28871536 0.85 CNR1 (0.39) CNR1CNR2KDM4EALDH1A1HPGD
SCHEMBL6235059 0.80 CNR1 (0.42) CNR1CNR2KDM4EALDH1A1HPGD
SCHEMBL15255041 0.77 CNR1 (0.43) CNR1CNR2KDM4EALDH1A1HPGD
SCHEMBL28277298 0.76 ALDH1A1 (0.36) KDM4EALDH1A1HPGDGAAPRKCI
SCHEMBL23387417 0.76 NOS2 (0.42) CNR1CNR2KDM4EALDH1A1HPGD
SCHEMBL981537 0.76 PRKCI (0.48) CNR1CNR2PRKCICYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101942087-B Metal ion-hyperbranched polyamidoamine complex catalyst and application thereof in preparation of polyphenyl ether in aqueous medium UNIV ZHEJIANG 2012-05-09 CN disclosed