Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 7/20 | 0.49 |
| ▸ | FAAH | O00519 | 4/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.42 |
| ▸ | GSK3A | P49840 | 2/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | IAPP | P10997 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20615288 | 0.84 | BACE1 (0.45) | BACE1TYRALOX5IAPPKDM4E | |
| SCHEMBL5930599 | 0.79 | MGLL (0.47) | MGLLFAAHPTGS1PTGS2GSK3A | |
| SCHEMBL21289229 | 0.79 | BACE1 (0.41) | BACE1TYRALOX5IAPPKDM4E | |
| SCHEMBL7603592 | 0.78 | KAT8 (0.48) | PTGS1PTGS2BACE1TYRALOX5 | |
| SCHEMBL7602848 | 0.78 | KAT8 (0.48) | PTGS1PTGS2BACE1TYRALOX5 | |
| SCHEMBL10399116 | 0.78 | KAT8 (0.48) | PTGS1PTGS2BACE1TYRALOX5 | |
| SCHEMBL4799742 | 0.78 | MGLL (0.67) | MGLLFAAHPTGS1PTGS2GSK3A | |
| SCHEMBL1024663 | 0.78 | HPGD (0.57) | BACE1TYRALOX5IAPPKDM4E | |
| SCHEMBL5072436 | 0.76 | MGLL (0.63) | MGLLFAAHPTGS1PTGS2GSK3A | |
| SCHEMBL1022454 | 0.76 | ALOX5 (0.60) | BACE1TYRALOX5IAPPHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102653579-B | Nitrile rubber and preparation method thereof | PETROCHINA CO LTD | 2013-12-04 | — | — | CN | claimed |
| CN-102653579-A | Nitrile rubber and preparation method thereof | PETROCHINA CO LTD | 2012-09-05 | — | — | CN | claimed |
| CN-103450397-A | Preparation method of nitrile rubber | PETROCHINA CO LTD | 2013-12-18 | — | — | CN | disclosed |
| CN-102653579-B | Nitrile rubber and preparation method thereof | PETROCHINA CO LTD | 2013-12-04 | — | — | CN | disclosed |
| CN-102653579-A | Nitrile rubber and preparation method thereof | PETROCHINA CO LTD | 2012-09-05 | — | — | CN | disclosed |