Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LPL | P06858 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
| ▸ | TACR2 | P21452 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28040851 | 0.86 | GPR3 (0.46) | GPR3PTGS2HSD11B1KCNH2CYP3A4 | |
| SCHEMBL26882681 | 0.75 | PTGS2 (0.53) | PTGS2CYP3A4GPR84ESR1ADRA2A | |
| SCHEMBL26882875 | 0.75 | PTGS2 (0.53) | PTGS2CYP3A4GPR84ESR1ADRA2A | |
| SCHEMBL23068703 | 0.75 | PTGS2 (0.53) | PTGS2CYP3A4GPR84ESR1ADRA2A | |
| SCHEMBL15409673 | 0.72 | KCNH2 (0.44) | GPR3PTGS2HSD11B1KCNH2CYP3A4 | |
| SCHEMBL15410370 | 0.72 | KCNH2 (0.44) | GPR3PTGS2HSD11B1KCNH2CYP3A4 | |
| SCHEMBL9122379 | 0.72 | PTGS2 (0.70) | PTGS2CYP3A4GPR84LPLLIPG | |
| SCHEMBL8560359 | 0.72 | PTGS2 (0.70) | PTGS2CYP3A4GPR84LPLLIPG | |
| SCHEMBL7628223 | 0.72 | PTGS2 (0.70) | PTGS2CYP3A4GPR84LPLLIPG | |
| SCHEMBL10318756 | 0.72 | PTGS2 (0.50) | PTGS2CYP3A4GPR84ESR1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102666561-A | Transition metal complex, preparation method for said transition metal complex, trimerization catalyst, preparation method for 1-hexene, preparation method for ethylene polymer, substituted cyclopentadiene compound, and preparation method for said su | SUMITOMO CHEMICAL CO | 2012-09-12 | — | — | CN | disclosed |