Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL286788 | 0.67 | MAPT (0.35) | MAPTSMN1; SMN2MEN1ALDH1A1RAB9A | |
| SCHEMBL286928 | 0.64 | ALDH1A1 (0.34) | SMN1; SMN2MEN1ALDH1A1RAB9AKMT2A | |
| SCHEMBL11213610 | 0.63 | KMT2A (0.49) | MAPTSMN1; SMN2MEN1ALDH1A1RAB9A | |
| SCHEMBL287118 | 0.62 | KMT2A (0.33) | MAPTSMN1; SMN2MEN1ALDH1A1RAB9A | |
| SCHEMBL27473615 | 0.59 | LMNA (0.31) | MAPT | |
| SCHEMBL661855 | 0.59 | LMNA (0.33) | MAPT | |
| SCHEMBL2789975 | 0.59 | MAPT (0.48) | MAPTSMN1; SMN2MEN1ALDH1A1RAB9A | |
| SCHEMBL6694136 | 0.58 | ALDH1A1 (0.56) | MAPTSMN1; SMN2MEN1ALDH1A1RAB9A | |
| SCHEMBL1844829 | 0.58 | MIF (0.43) | MAPTSMN1; SMN2MEN1ALDH1A1RAB9A | |
| SCHEMBL1847472 | 0.57 | DAO (0.48) | MAPTSMN1; SMN2MEN1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427432-A2 | NOVEL HETEROCYCLIC COMPOUNDS | Torrent Pharmaceuticals Limited (IN) | 2012-03-14 | — | — | EP | claimed |
| WO-2010128528-A2 | NOVEL HETEROCYCLIC COMPOUNDS | TORRENT PHARMACEUTICALS LIMITED (IN) | 2010-11-11 | — | — | WO | claimed |