Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL288004 | 0.88 | ALDH1A1 (0.48) | MAPTALDH1A1SMN1; SMN2HTTNPSR1 | |
| SCHEMBL287518 | 0.84 | ALDH1A1 (0.35) | MAPTALDH1A1SMN1; SMN2HTTNPSR1 | |
| SCHEMBL287274 | 0.83 | ALDH1A1 (0.33) | MAPTALDH1A1SMN1; SMN2HTTTSHR | |
| SCHEMBL287307 | 0.80 | ALDH1A1 (0.39) | MAPTALDH1A1SMN1; SMN2TSHRLMNA | |
| SCHEMBL287408 | 0.77 | RAB9A (0.43) | MAPTALDH1A1SMN1; SMN2TSHRLMNA | |
| SCHEMBL287419 | 0.73 | NPC1 (0.41) | MAPTALDH1A1SMN1; SMN2HTTTSHR | |
| SCHEMBL287774 | 0.72 | USP30 (0.36) | MAPTALDH1A1SMN1; SMN2HTTMCOLN3 | |
| SCHEMBL287767 | 0.72 | HPGD (0.42) | ALDH1A1TSHRTDP1MEN1KMT2A | |
| SCHEMBL287139 | 0.71 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2HTTNPSR1TSHR | |
| SCHEMBL287825 | 0.70 | ALDH1A1 (0.34) | MAPTALDH1A1SMN1; SMN2TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427432-A2 | NOVEL HETEROCYCLIC COMPOUNDS | Torrent Pharmaceuticals Limited (IN) | 2012-03-14 | — | — | EP | claimed |
| WO-2010128528-A2 | NOVEL HETEROCYCLIC COMPOUNDS | TORRENT PHARMACEUTICALS LIMITED (IN) | 2010-11-11 | — | — | WO | claimed |