Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL287368 | 0.90 | MIF (0.34) | LMNAPOLBMAPTMIF | |
| SCHEMBL7807381 | 0.89 | MAPT (0.32) | LMNAPOLBMAPTMIF | |
| SCHEMBL27473615 | 0.80 | LMNA (0.31) | LMNAPOLBMAPTMIF | |
| SCHEMBL287773 | 0.79 | ALDH1A1 (0.39) | LMNAPOLBMAPT | |
| SCHEMBL662691 | 0.76 | KMT2A (0.37) | LMNAPOLBMAPT | |
| SCHEMBL660526 | 0.74 | KAT6A (0.35) | MAPT | |
| SCHEMBL658639 | 0.72 | ALDH1A1 (0.39) | LMNAMAPT | |
| SCHEMBL297855 | 0.71 | ALDH1A1 (0.42) | LMNAPOLBMAPT | |
| SCHEMBL6230659 | 0.68 | KMT2A (0.47) | POLBMAPTMIF | |
| Bromide SCHEMBL1194167 | 0.67 | KMT2A (0.48) | POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120046317-A1 | NOVEL HETEROCYCLIC COMPOUNDS | DUTT CHAITANYA (IN) | 2012-02-23 | — | — | US | claimed |
| US-20120046317-A1 | NOVEL HETEROCYCLIC COMPOUNDS | DUTT CHAITANYA (IN) | 2012-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046317-A1 | NOVEL HETEROCYCLIC COMPOUNDS | AGER, REN, AGT | LMNA 123/4885POLB 2267/4885MAPT 61/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.