Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GSTP1 | P09211 | 3/20 | 0.39 |
| ▸ | GSTM2 | P28161 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8944099 | 0.77 | ALDH1A1 (0.59) | ALDH1A1MAPTRAB9ACA2L3MBTL1 | |
| SCHEMBL8446872 | 0.76 | ALDH1A1 (0.58) | ALDH1A1MAPTRAB9ACA2L3MBTL1 | |
| SCHEMBL10888237 | 0.76 | ALDH1A1 (0.58) | ALDH1A1MAPTRAB9ACA2L3MBTL1 | |
| SCHEMBL12695302 | 0.75 | TSHR (0.68) | ALDH1A1MAPTRAB9AL3MBTL1KMT2A | |
| SCHEMBL11705097 | 0.75 | GPR35 (0.51) | ALDH1A1KMT2ASMN1; SMN2LMNAMAPK1 | |
| SCHEMBL8444661 | 0.75 | HTT (0.52) | ALDH1A1MAPTRAB9ACA2L3MBTL1 | |
| SCHEMBL8427051 | 0.74 | CA2 (0.62) | ALDH1A1MAPTRAB9ACA2L3MBTL1 | |
| SCHEMBL8540296 | 0.74 | CA2 (0.60) | ALDH1A1MAPTRAB9ACA2L3MBTL1 | |
| SCHEMBL9656947 | 0.74 | ALDH1A1 (0.60) | ALDH1A1MAPTCA2KMT2ASMN1; SMN2 | |
| SCHEMBL29221076 | 0.74 | ATM (0.51) | ALDH1A1MAPTTDP1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101792525-B | Conjugated biological molecules and their preparation | POLYTHERICS LTD | 2012-06-06 | — | — | CN | disclosed |