Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 3/20 | 0.54 |
| ▸ | BACE1 | P56817 | 2/20 | 0.44 |
| ▸ | GSTP1 | P09211 | 4/20 | 0.44 |
| ▸ | GSTM2 | P28161 | 4/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10888237 | 0.83 | ALDH1A1 (0.58) | ALDH1A1MAPTRAB9AL3MBTL1CA2 | |
| SCHEMBL8446872 | 0.83 | ALDH1A1 (0.58) | ALDH1A1MAPTRAB9AL3MBTL1CA2 | |
| SCHEMBL8540296 | 0.81 | CA2 (0.60) | ALDH1A1MAPTRAB9AL3MBTL1CA2 | |
| SCHEMBL7458037 | 0.78 | CA2 (0.57) | ALDH1A1MAPTRAB9AL3MBTL1CA2 | |
| SCHEMBL28798451 | 0.77 | ALDH1A1 (0.52) | ALDH1A1MAPTRAB9AL3MBTL1CA2 | |
| SCHEMBL29662266 | 0.76 | BACE1 (0.45) | ALDH1A1BACE1EGFRGPR35NPSR1 | |
| SCHEMBL2935849 | 0.76 | BACE1 (0.45) | ALDH1A1BACE1EGFRGPR35NPSR1 | |
| SCHEMBL8444661 | 0.76 | HTT (0.52) | ALDH1A1MAPTRAB9AL3MBTL1CA2 | |
| SCHEMBL832001 | 0.74 | ALDH1A1 (0.71) | ALDH1A1MAPTL3MBTL1CA2GPR35 | |
| SCHEMBL12291532 | 0.73 | CA2 (0.63) | ALDH1A1MAPTRAB9AL3MBTL1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0146007-B1 | PROCESS FOR THE PREPARATION OF 5-HYDROXYETHYLSULPHONYL-2-AMINOPHENOL (OR ETHERS) | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-12-30 | — | — | EP | claimed |
| US-5503640-A | ALKYLTHIO PARA-AMINOPHENOLS IN AQUEOUS VEHICLE FOR DYEING HUMAN HAIR | L'OREAL (FR) | 1996-04-02 | — | — | US | disclosed |
| US-5364413-A | Oxidation color dyes for hair | L'OREAL (FR) | 1994-11-15 | — | — | US | disclosed |
| US-5084067-A | Indoaniline dyes for hair dyes | L'OREAL (FR) | 1992-01-28 | — | — | US | disclosed |