SCHEMBL28798974

SCHEMBL28798974

Cc1c(C=O)cccc1C1CCCCC1

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 2/20 0.41
ALDH1A1 P00352 3/20 0.38
TSHR P16473 1/20 0.38
KCNJ1 P48048 1/20 0.38
PTGS2 P35354 1/20 0.38
CEL P19835 2/20 0.37
PTGDR2 Q9Y5Y4 1/20 0.36
MEN1 O00255 1/20 0.35
LMNA P02545 1/20 0.35
THRB P10828 1/20 0.35
BLM P54132 1/20 0.35
KMT2A Q03164 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
HTR1A P08908 1/20 0.35
HTR7 P34969 1/20 0.35
HTR6 P50406 2/20 0.33
PSMB5 P28074 1/20 0.33
SRC P12931 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL197356 0.82 MEN1 (0.46) ALDH1A1TSHRPTGS2CELPTGDR2
SCHEMBL21647623 0.82 MEN1 (0.46) ALDH1A1TSHRPTGS2CELPTGDR2
SCHEMBL22284134 0.82 MEN1 (0.46) ALDH1A1TSHRPTGS2CELPTGDR2
SCHEMBL14237042 0.82 MEN1 (0.46) ALDH1A1TSHRPTGS2CELPTGDR2
SCHEMBL14236917 0.82 MEN1 (0.46) ALDH1A1TSHRPTGS2CELPTGDR2
SCHEMBL11675315 0.82 MEN1 (0.46) ALDH1A1TSHRPTGS2CELPTGDR2
SCHEMBL31240954 0.81 HTR2C (0.52) HTR2CPTGS2CELPTGDR2HTR1A
SCHEMBL28480307 0.81 CEL (0.38) ALDH1A1PTGS2CELPTGDR2MEN1
SCHEMBL31415807 0.80 LMNA (0.48) HTR2CALDH1A1TSHRPTGS2CEL
SCHEMBL547607 0.80 LMNA (0.48) HTR2CALDH1A1TSHRPTGS2CEL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102754033-A Underlayer film material and method for forming multilayer resist pattern MITSUBISHI GAS CHEMICAL CO 2012-10-24 CN disclosed