Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.32 |
| ▸ | ARG1 | P05089 | 1/20 | 0.30 |
| ▸ | ARG2 | P78540 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL994468 | 0.84 | ARG1 (0.30) | ARG1ARG2 | |
| SCHEMBL914574 | 0.81 | CHRM3 (0.39) | CHRM2CHRM1CHRM3 | |
| SCHEMBL27988422 | 0.79 | KMT2A (0.36) | CHRM2CHRM1CHRM3 | |
| Hydrochloric Acid SCHEMBL28914966 | 0.79 | CHRM3 (0.38) | CHRM2CHRM1CHRM3 | |
| SCHEMBL25134114 | 0.75 | — | — | |
| SCHEMBL27761386 | 0.75 | CYP19A1 (0.39) | ATMCHRM3 | |
| SCHEMBL20617836 | 0.74 | SLC6A1 (0.33) | CHRM1CHRM3 | |
| SCHEMBL27598186 | 0.74 | SLC6A1 (0.33) | CHRM1CHRM3 | |
| SCHEMBL27653752 | 0.74 | SLC6A1 (0.33) | CHRM1CHRM3 | |
| SCHEMBL24670611 | 0.73 | HRH3 (0.40) | CHRM2CHRM1CHRM3ARG1ARG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102939283-A | Indazole compounds useful as ketohexokinase inhibitors | JANSSEN PHARMACEUTICA NV | 2013-02-20 | — | — | CN | disclosed |