SCHEMBL914574

SCHEMBL914574

CC(C)(C)C(=O)OC1CCNCC1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM3 P20309 6/20 0.39
GABRA1 P14867 2/20 0.37
TSHR P16473 2/20 0.37
GABRG2 P18507 2/20 0.37
GABRB3 P28472 2/20 0.37
GABRA5 P31644 2/20 0.37
GABRA3 P34903 2/20 0.37
GABRA2 P47869 2/20 0.37
GABRA6 Q16445 2/20 0.37
GABRP O00591 1/20 0.37
GABRD O14764 1/20 0.37
GABRB1 P18505 1/20 0.37
GABRB2 P47870 1/20 0.37
GABRA4 P48169 1/20 0.37
GABRE P78334 1/20 0.37
PMP22 Q01453 1/20 0.37
GABRG1 Q8N1C3 1/20 0.37
GABRG3 Q99928 1/20 0.37
GABRQ Q9UN88 1/20 0.37
CYP19A1 P11511 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28914966 0.98 CHRM3 (0.38) CHRM3GABRA1TSHRGABRG2GABRB3
SCHEMBL27761386 0.93 CYP19A1 (0.39) CHRM3GABRA1TSHRGABRG2GABRB3
SCHEMBL27653752 0.88 SLC6A1 (0.33) CHRM3GABRA1GABRA5GABRB2GABRA4
SCHEMBL20617836 0.88 SLC6A1 (0.33) CHRM3GABRA1GABRA5GABRB2GABRA4
SCHEMBL27598186 0.88 SLC6A1 (0.33) CHRM3GABRA1GABRA5GABRB2GABRA4
SCHEMBL17886845 0.84 CYP19A1 (0.41) CHRM3CYP19A1EPHX1
SCHEMBL14648562 0.84 GABRP (0.34) CHRM3GABRA1TSHRGABRG2GABRB3
SCHEMBL13641699 0.81 TPSAB1 (0.34) CHRM3GABRA1TSHRGABRG2GABRB3
SCHEMBL28801029 0.81 ATM (0.34) CHRM3CHRM2CHRM1
SCHEMBL13073268 0.80 CYP19A1 (0.46) CHRM3CYP19A1EPHX1CHRM2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 256 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117567498-A Sodium hydride suspension and application thereof in flow chemical reaction 武汉药明康德新药开发有限公司 2024-02-20 CN claimed
CN-117069063-A Sodium hydride suspension and application thereof in flow chemical reaction 武汉药明康德新药开发有限公司 2023-11-17 CN claimed
US-20230010299-A1 HETEROCYCLIC TRPML1 AGONISTS LIBRA THERAPEUTICS, INC. 2023-01-12 US claimed
EP-4058145-A1 HETEROCYCLIC TRPML1 AGONISTS Libra Therapeutics, Inc. (US) 2022-09-21 EP claimed
WO-2021094974-A1 HETEROCYCLIC TRPML1 AGONISTS LIBRA THERAPEUTICS, INC. (US) 2021-05-20 WO claimed
EP-3821947-A1 HETEROCYCLIC TRPML1 AGONISTS Libra Therapeutics, Inc. (US) 2021-05-19 EP claimed
CN-102236253-B Multi-phase high-silicon photoresist imaging method for micro-photoetching process, multi-phase high-silicon photoresist and use WEIFANG XINGTAIKE MICROELECTRONIC MATERIALS CO LTD 2012-11-07 CN claimed
CN-102236253-A Multi-phase high-silicon photoresist imaging method for micro-photoetching process, multi-phase high-silicon photoresist and use WEIFANG XINGTAIKE MICROELECTRONIC MATERIALS CO LTD 2011-11-09 CN claimed
CN-117658986-A Preparation method of AR antagonist TRC-253 湖南师范大学 2024-03-08 CN disclosed
CN-117567498-A Sodium hydride suspension and application thereof in flow chemical reaction 武汉药明康德新药开发有限公司 2024-02-20 CN disclosed
CN-117069063-A Sodium hydride suspension and application thereof in flow chemical reaction 武汉药明康德新药开发有限公司 2023-11-17 CN disclosed
US-20230030115-A1 RHO-ASSOCIATED PROTEIN KINASE INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND PREPARATION METHOD AND USE THEREOF BEIJING TIDE PHARMACEUTICAL CO LTD (CN) 2023-02-02 US disclosed
US-20230010299-A1 HETEROCYCLIC TRPML1 AGONISTS LIBRA THERAPEUTICS, INC. 2023-01-12 US disclosed
EP-4058145-A1 HETEROCYCLIC TRPML1 AGONISTS Libra Therapeutics, Inc. (US) 2022-09-21 EP disclosed
CN-1615306-A C-5 modified indazolylpyrrolotriazines BRISTOL MYERS SQUIBB CO (US) 2005-05-11 CN disclosed
CN-1509286-A Metalloprotease inhibitors 2004-06-30 CN disclosed
CN-1290266-A Benzofuran-4-carboxamides and their therapeutical use DARWIN DISCOVERY LTD (GB) 2001-04-04 CN disclosed
CN-1211991-A Compounds with growth hormone releasing properties NOVO NORDISK AS (DK) 1999-03-24 CN disclosed
CN-1125575-A Adhesion receptor antagonists MERCK PATENT GMBH (DE) 1996-07-03 CN disclosed
CN-1111630-A Adhesion receptor antagonists MERCK PATENT GMBH (DE) 1995-11-15 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230030115-A1 RHO-ASSOCIATED PROTEIN KINASE INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND PREPARATION METHOD AND USE THEREOF ROCK1, ROCK2, RHOA CHRM3 2057/4885GABRA1 4423/4885TSHR 4479/4885
US-20230010299-A1 HETEROCYCLIC TRPML1 AGONISTS TRPM7, TRPM2, TRPM5 CHRM3 355/4885GABRA1 909/4885TSHR 1067/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.