Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.72 |
| ▸ | RAB9A | P51151 | 7/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.72 |
| ▸ | MEN1 | O00255 | 2/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.72 |
| ▸ | LMNA | P02545 | 2/20 | 0.72 |
| ▸ | RECQL | P46063 | 1/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.72 |
| ▸ | SCD | O00767 | 1/20 | 0.68 |
| ▸ | AGER | Q15109 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.66 |
| ▸ | CASP3 | P42574 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.66 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.66 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL27908399 | 0.98 | NPC1 (0.70) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL4290771 | 0.85 | NPC1 (0.79) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL4293350 | 0.84 | RAB9A (0.77) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL3223685 | 0.84 | RAB9A (1.00) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL2307971 | 0.84 | RAB9A (0.72) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL8797071 | 0.84 | NPC1 (0.62) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL3200814 | 0.84 | NPC1 (1.00) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL995829 | 0.83 | NPC1 (1.00) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL2628996 | 0.83 | NPC1 (0.76) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL3792337 | 0.83 | RAB9A (0.62) | NPC1RAB9ASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102936229-A | 4-tertiary butyl-5-benzyl-2-acetyl aminothiazole with insecticidal activity and preparation method | UNIV HUNAN | 2013-02-20 | — | — | CN | disclosed |