Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 1.00 |
| ▸ | RAB9A | P51151 | 8/20 | 1.00 |
| ▸ | SCD | O00767 | 1/20 | 0.88 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.78 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.78 |
| ▸ | POLB | P06746 | 1/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.71 |
| ▸ | LMNA | P02545 | 4/20 | 0.71 |
| ▸ | MEN1 | O00255 | 3/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.71 |
| ▸ | RECQL | P46063 | 1/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | METAP2 | P50579 | 1/20 | 0.69 |
| ▸ | METAP1 | P53582 | 1/20 | 0.69 |
| ▸ | AGER | Q15109 | 1/20 | 0.66 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.64 |
| ▸ | HSPA9 | P38646 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27594584 | 0.98 | NPC1 (0.97) | NPC1RAB9ASCDKCNK3KCNK9 | |
| SCHEMBL16562033 | 0.94 | SCD (1.00) | NPC1RAB9ASCDKCNK3KCNK9 | |
| SCHEMBL4285954 | 0.92 | NPC1 (0.85) | NPC1RAB9ASCDKCNK3KCNK9 | |
| SCHEMBL4290771 | 0.88 | NPC1 (0.79) | NPC1RAB9ASCDKCNK3KCNK9 | |
| Nitrobenzene SCHEMBL27694792 | 0.87 | NPC1 (0.82) | NPC1RAB9ASCDKCNK3KCNK9 | |
| SCHEMBL11059973 | 0.87 | RAB9A (0.77) | NPC1RAB9ASCDKCNK3KCNK9 | |
| SCHEMBL2628996 | 0.86 | NPC1 (0.76) | NPC1RAB9ASCDKCNK3KCNK9 | |
| SCHEMBL14082184 | 0.85 | NPC1 (0.74) | NPC1RAB9ASCDKCNK3KCNK9 | |
| SCHEMBL4636379 | 0.85 | NPC1 (0.73) | NPC1RAB9ASCDKCNK3KCNK9 | |
| SCHEMBL4600878 | 0.85 | NPC1 (0.73) | NPC1RAB9ASCDKCNK3KCNK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 241 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3623372-B1 | PYRROLO AND PYRAZOLOPYRIMIDINES AS UBIQUITIN-SPECIFIC PROTEASE 7 INHIBITORS | VALO HEALTH INC (US) | 2026-02-04 | — | — | EP | claimed |
| EP-4580404-A2 | SULFONAMIDE APYRASE INHIBITORS | Texas Crop Science, Inc. (US) | 2025-07-09 | — | — | EP | claimed |
| WO-2025121320-A1 | PROPHYLACTIC OR THERAPEUTIC AGENT FOR POLYCYSTIC KIDNEY DISEASE | 国立大学法人山口大学 | 2025-06-12 | — | — | WO | claimed |
| CN-120058701-A | Thioether structure-containing targeted PHGDH active molecular probe, preparation method and application thereof | 中国药科大学 | 2025-05-30 | — | — | CN | claimed |
| CN-112480104-B | Nitrazonit derivative and medical application thereof | 绍兴君科臻元医药科技有限公司 | 2024-06-18 | — | — | CN | claimed |
| US-20240099300-A1 | SULFONAMIDE APYRASE INHIBITORS | TEXAS CROP SCIENCE, INC. | 2024-03-28 | — | — | US | claimed |
| WO-2024050041-A2 | SULFONAMIDE APYRASE INHIBITORS | TEXAS CROP SCIENCE (US) | 2024-03-07 | — | — | WO | claimed |
| EP-3324954-B1 | AMINONAPTHOQUINONE COMPOUNDS AND PHARMACEUTICAL COMPOSITION FOR BLOCKING UBIQUITINATION-PROTEASOME SYSTEM IN DISEASES | CALGENT BIOTECHNOLOGY CO LTD (TW) | 2022-03-09 | — | — | EP | claimed |
| CN-105030797-B | The composition of a kind of anti-japanese encephalitis virus infection and its application | 中国农业科学院上海兽医研究所 | 2018-10-23 | — | — | CN | claimed |
| CN-108602827-A | Imidazopyrazine inhibitors of Bruton's tyrosine kinase | 安塞塔制药公司 | 2018-09-28 | — | — | CN | claimed |
| CN-1870996-A | N-thiazol-2-yl-benzamide derivatives | LUNDBECK & CO AS H (DK) | 2006-11-29 | — | — | CN | claimed |
| EP-1694673-A1 | NOVEL THIAZOLE DERIVATES | F.HOFFMANN-LA ROCHE AG (CH) | 2006-08-30 | — | — | EP | claimed |
| US-20050153962-A1 | Thiazole derivatives | HOFFMANN-LA ROCHE INC. | 2005-07-14 | — | — | US | claimed |
| WO-2005058887-A1 | NOVEL THIAZOLE DERIVATES | F. HOFFMANN-LA ROCHE AG (CH) | 2005-06-30 | — | — | WO | claimed |
| EP-0934938-B1 | SUBSTITUTED BENZOYLAMINOTHIAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME | ZERIA PHARM CO LTD (JP) | 2003-01-15 | — | — | EP | claimed |
| EP-1102743-B1 | AMIDE DERIVATIVES WHICH ARE USEFUL AS CYTOKINE INHIBITORS | ASTRAZENECA AB (SE) | 2002-07-24 | — | — | EP | claimed |
| CN-1072652-C | Substd. benzoylaminothiazole derivatives and drugs containing same | ZERIA PHARM CO LTD (JP) | 2001-10-10 | — | — | CN | claimed |
| US-6121301-A | ADMINISTERING TO PREVENT OR TREAT GASTROINTESTINAL DYSMOTILITY; COMPOUNDS SUCH AS 2-((N-(3-CYANOBENZOYL)AMINO)-4-((3-DIISOPROPYLAMINOPROPYL)AMINOCARBONYL)-1,3-THIAZOLE | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2000-09-19 | — | — | US | claimed |
| CN-1234028-A | Substd. benzoylaminothiazole derivatives and drugs containing same | ZERIA PHARM CO LTD (JP) | 1999-11-03 | — | — | CN | claimed |
| EP-0934938-A1 | SUBSTITUTED BENZOYLAMINOTHIAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1999-08-11 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240099300-A1 | SULFONAMIDE APYRASE INHIBITORS | APEH, ARSA, DNPEP | NPC1 3337/4885RAB9A 1777/4885SCD 152/4885 |
| US-20050153962-A1 | Thiazole derivatives | CNR1, CNR2, GPR119 | NPC1 313/4885RAB9A 1847/4885SCD 1740/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.