SCHEMBL28801221

SCHEMBL28801221

NNC(=O)c1ccccc1CF

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSD P07339 2/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
CA9 Q16790 1/20 0.52
ALDH1A1 P00352 6/20 0.50
P2RX7 Q99572 1/20 0.50
GAA P10253 3/20 0.47
MAPT P10636 3/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
MITF O75030 1/20 0.47
NCOA1 Q15788 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
NCOA3 Q9Y6Q9 1/20 0.47
GFER P55789 2/20 0.45
HPGD P15428 3/20 0.44
LMNA P02545 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
BCAT2 O15382 1/20 0.44
ADRB2 P07550 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3135538 0.83 CTSD (0.56) CTSDCA1CA2CA9ALDH1A1
SCHEMBL3412935 0.83 GAA (0.62) CTSDCA1CA2CA9ALDH1A1
SCHEMBL239328 0.82 CTSD (0.63) CTSDCA1CA2CA9ALDH1A1
SCHEMBL30547074 0.82 CTSD (0.63) CTSDCA1CA2CA9ALDH1A1
SCHEMBL28918514 0.81 CTSD (0.46) CTSDALDH1A1GAAKMT2AHPGD
SCHEMBL9541052 0.81 ALDH1A1 (0.54) ALDH1A1GAAHPGDLMNAL3MBTL1
SCHEMBL3828592 0.81 KDM4E (0.50) ALDH1A1GAAMAPTMEN1KMT2A
Hydroxyamine SCHEMBL14300671 0.80 CTSD (0.61) CTSDCA1CA2CA9ALDH1A1
Hydrazine SCHEMBL14300720 0.80 CTSD (0.61) CTSDCA1CA2CA9ALDH1A1
Hydrochloric Acid SCHEMBL6692325 0.80 CTSD (0.61) CTSDCA1CA2CA9ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110041226-B Compound with AIE characteristics and preparation method and application thereof 江苏萨瑞斯医疗科技有限公司 2022-05-31 CN disclosed