Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | CTSD | P07339 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3135538 | 0.83 | CTSD (0.56) | GAAHPGDLMNAL3MBTL1CTSD | |
| SCHEMBL1098843 | 0.83 | GAA (0.62) | GAAHPGDLMNAL3MBTL1CA1 | |
| SCHEMBL28801221 | 0.83 | CTSD (0.52) | GAAHPGDLMNAL3MBTL1CTSD | |
| SCHEMBL5256509 | 0.82 | HPGD (0.67) | GAAHPGDLMNAL3MBTL1CA1 | |
| SCHEMBL239328 | 0.82 | CTSD (0.63) | GAACTSDCA1CA2CA9 | |
| SCHEMBL30547074 | 0.82 | CTSD (0.63) | GAACTSDCA1CA2CA9 | |
| SCHEMBL15129274 | 0.82 | HPGD (0.61) | GAAHPGDLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL22596733 | 0.82 | HPGD (0.61) | GAAHPGDLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL6868432 | 0.82 | HPGD (0.66) | GAAHPGDLMNAL3MBTL1CA1 | |
| SCHEMBL16772098 | 0.82 | HPGD (0.61) | GAAHPGDLMNAL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104031037-B | Formanilide compound containing 1, 3, 4-oxadiazole structure as well as preparation method and application thereof | 南京工业大学 | 2017-01-18 | — | — | CN | disclosed |
| CN-104031037-A | Formanilide compound containing 1,3, 4-oxadiazole structure as well as preparation method and application thereof | NANJING UNIVERSITY OF TECHNOLOGY | 2014-09-10 | — | — | CN | disclosed |
| EP-2260028-A2 | SELECTIVE ANDROGEN RECEPTOR MODULATORS | Radius Health, Inc. (US) | 2010-12-15 | — | — | EP | disclosed |
| WO-2009105214-A2 | SELECTIVE ANDROGEN RECEPTOR MODULATORS | RADIUS HEALTH, INC. (US) | 2009-08-27 | — | — | WO | disclosed |
| US-20090156509-A1 | Tri-peptide Inhibitors of Serine Elastases | ACCUTHERA, INC. (US) | 2009-06-18 | — | — | US | disclosed |
| US-20080139560-A1 | Ion Channel Modulators | SCION PHARMACEUTICALS, INC. | 2008-06-12 | — | — | US | disclosed |
| US-20070281937-A1 | Ion Channel Modulators | SCION PHARMACEUTICALS, INC. | 2007-12-06 | — | — | US | disclosed |
| WO-2005097112-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2005-10-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070281937-A1 | Ion Channel Modulators | CACNA1B, CACNA1C, TRPV1 | GAA 1560/4885HPGD 2634/4885LMNA 1903/4885 |
| US-20080139560-A1 | Ion Channel Modulators | CACNA1B, CACNA1C, TRPV1 | GAA 1560/4885HPGD 2634/4885LMNA 1903/4885 |
| US-20090156509-A1 | Tri-peptide Inhibitors of Serine Elastases | SCTR, CTRC, SERPINB1 | GAA 2476/4885HPGD 2593/4885LMNA 3222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.