Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | STAT1 | P42224 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 6/20 | 0.44 |
| ▸ | CA1 | P00915 | 6/20 | 0.44 |
| ▸ | CA2 | P00918 | 6/20 | 0.44 |
| ▸ | CA9 | Q16790 | 6/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.43 |
| ▸ | MERTK | Q12866 | 1/20 | 0.43 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.43 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | CLK2 | P49760 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL725129 | 0.87 | PLA2G4A (0.57) | MAPTALDH1A1NPC1STAT1RAB9A | |
| SCHEMBL10467225 | 0.85 | PLA2G4A (0.59) | MAPTALDH1A1NPC1STAT1RAB9A | |
| Hydrochloric Acid SCHEMBL28780137 | 0.82 | FLT3 (0.37) | MAPTALDH1A1NPC1RAB9AFLT3 | |
| SCHEMBL10465516 | 0.81 | CYP1A2 (0.64) | MAPTALDH1A1NPC1RAB9ACA12 | |
| SCHEMBL11498389 | 0.80 | PDE5A (0.50) | MAPTALDH1A1NPC1STAT1RAB9A | |
| SCHEMBL792862 | 0.79 | MAPT (0.45) | MAPTALDH1A1NPC1STAT1RAB9A | |
| SCHEMBL4099165 | 0.74 | RAB9A (0.59) | MAPTALDH1A1NPC1STAT1RAB9A | |
| SCHEMBL725866 | 0.74 | HPGD (0.53) | HPGD | |
| SCHEMBL16397272 | 0.74 | ACHE (0.54) | MAPTNPC1RAB9ACA12CA1 | |
| SCHEMBL1837764 | 0.74 | ECE1 (0.44) | ALDH1A1CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7799738-B2 | Insecticidal 2-acylaminothiazole-4-carboxamides | BAYER CROPSCIENCE AG (DE) | 2010-09-21 | — | — | US | claimed |
| US-20080300136-A1 | Insecticidal 2-Acylaminothiazole-4-Carboxamides | BAYER CROPSCIENCE AG (DE) | 2008-12-04 | — | — | US | claimed |
| EP-1963290-A1 | INSECTICIDAL 2 -ACYLAMINOTHIAZOLE-4 -CARBOXAMIDES | Bayer CropScience Aktiengesellschaft (DE) | 2008-09-03 | — | — | EP | claimed |
| WO-2007051560-A1 | INSECTICIDAL 2 -ACYLAMINOTHIAZOLE-4 -CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2007-05-10 | — | — | WO | claimed |
| US-7799738-B2 | Insecticidal 2-acylaminothiazole-4-carboxamides | BAYER CROPSCIENCE AG (DE) | 2010-09-21 | — | — | US | disclosed |
| US-7799738-B2 | Insecticidal 2-acylaminothiazole-4-carboxamides | BAYER CROPSCIENCE AG (DE) | 2010-09-21 | — | — | US | disclosed |
| US-7799738-B2 | Insecticidal 2-acylaminothiazole-4-carboxamides | BAYER CROPSCIENCE AG (DE) | 2010-09-21 | — | — | US | disclosed |
| WO-2010012793-A1 | FUNGICIDE AMINOTHIAZOLE DERIVATIVES | BAYER CROPSCIENCE SA (FR) | 2010-02-04 | — | — | WO | disclosed |
| CN-101351457-A | Insecticidal 2-acylaminothiazole-4-carboxamides | BAYER CROPSCIENCE AG (DE) | 2009-01-21 | — | — | CN | disclosed |
| CN-101351457-A | Insecticidal 2-acylaminothiazole-4-carboxamides | BAYER CROPSCIENCE AG (DE) | 2009-01-21 | — | — | CN | disclosed |
| US-20080300136-A1 | Insecticidal 2-Acylaminothiazole-4-Carboxamides | BAYER CROPSCIENCE AG (DE) | 2008-12-04 | — | — | US | disclosed |
| US-20080300136-A1 | Insecticidal 2-Acylaminothiazole-4-Carboxamides | BAYER CROPSCIENCE AG (DE) | 2008-12-04 | — | — | US | disclosed |
| US-20080300136-A1 | Insecticidal 2-Acylaminothiazole-4-Carboxamides | BAYER CROPSCIENCE AG (DE) | 2008-12-04 | — | — | US | disclosed |
| EP-1963290-A1 | INSECTICIDAL 2 -ACYLAMINOTHIAZOLE-4 -CARBOXAMIDES | Bayer CropScience Aktiengesellschaft (DE) | 2008-09-03 | — | — | EP | disclosed |
| EP-1963290-A1 | INSECTICIDAL 2 -ACYLAMINOTHIAZOLE-4 -CARBOXAMIDES | Bayer CropScience Aktiengesellschaft (DE) | 2008-09-03 | — | — | EP | disclosed |
| JP-2007119416-A | INSECTICIDAL 2-ACYLAMINOTHIAZOLE-4-CARBOXAMIDES | BAYER CROPSCIENCE AG | 2007-05-17 | — | — | JP | disclosed |
| WO-2007051560-A1 | INSECTICIDAL 2 -ACYLAMINOTHIAZOLE-4 -CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2007-05-10 | — | — | WO | disclosed |
| WO-2007051560-A1 | INSECTICIDAL 2 -ACYLAMINOTHIAZOLE-4 -CARBOXAMIDES | BAYER CROPSCIENCE AG (DE) | 2007-05-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080300136-A1 | Insecticidal 2-Acylaminothiazole-4-Carboxamides | AADAC, HDHD5, HRH4 | MAPT 4652/4885ALDH1A1 757/4885NPC1 2323/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.