Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGBL2 | Q5U5Z8 | 2/20 | 0.42 |
| ▸ | SLC13A5 | Q86YT5 | 3/20 | 0.41 |
| ▸ | SLC13A2 | Q13183 | 1/20 | 0.41 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | CCNC | P24863 | 1/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12218698 | 0.79 | DPP4 (0.40) | AGBL2SLC13A5SLC13A2SLC13A3DPP4 | |
| SCHEMBL1915182 | 0.77 | ATM (0.41) | SLC13A5SLC13A2SLC13A3DPP4CCNC | |
| SCHEMBL31168612 | 0.77 | KDM4E (0.41) | CCNCCDK8NPSR1KDM4ETSHR | |
| SCHEMBL28801469 | 0.75 | SLC13A5 (0.43) | SLC13A5SLC13A2SLC13A3CCNCCDK8 | |
| SCHEMBL27383378 | 0.70 | AMY1A (0.46) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL25168224 | 0.69 | AGBL2 (0.51) | AGBL2SLC13A5SLC13A2SLC13A3GABRR1 | |
| SCHEMBL17653807 | 0.69 | AGBL2 (0.60) | AGBL2GABRR1KDM4EALDH1A1MAPT | |
| SCHEMBL30391135 | 0.69 | AGBL2 (0.51) | AGBL2SLC13A5SLC13A2SLC13A3GABRR1 | |
| SCHEMBL27877899 | 0.69 | AGBL2 (0.41) | AGBL2DPP4CCNCCDK8GABRR1 | |
| SCHEMBL5348731 | 0.68 | TAAR1 (0.50) | NPSR1TSHRALDH1A1SMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102762560-A | Disubstituted heteroaryl-fused pyridines | NOVARTIS AG | 2012-10-31 | — | — | CN | disclosed |