Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC13A5 | Q86YT5 | 3/20 | 0.43 |
| ▸ | SLC13A2 | Q13183 | 1/20 | 0.43 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.43 |
| ▸ | CCNC | P24863 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1135121 | 0.81 | SLC13A5 (0.43) | SLC13A5SLC13A2SLC13A3KDM4ELMNA | |
| SCHEMBL1915182 | 0.77 | ATM (0.41) | SLC13A5SLC13A2SLC13A3CCNCCDK8 | |
| SCHEMBL28801471 | 0.75 | AGBL2 (0.42) | SLC13A5SLC13A2SLC13A3CCNCCDK8 | |
| SCHEMBL27465508 | 0.72 | NOS3 (0.41) | SLC13A5SLC13A2SLC13A3LMNAALDH1A1 | |
| SCHEMBL31168612 | 0.71 | KDM4E (0.41) | CCNCCDK8KDM4ELMNAMAPT | |
| SCHEMBL25168223 | 0.69 | LMNA (0.37) | SLC13A5SLC13A2SLC13A3KDM4ELMNA | |
| SCHEMBL5348731 | 0.68 | TAAR1 (0.50) | LMNAMAPTHSD17B10ALDH1A1HTT | |
| SCHEMBL12808519 | 0.68 | NPSR1 (0.61) | CCNCCDK8KDM4ELMNAMAPT | |
| SCHEMBL12218698 | 0.67 | DPP4 (0.40) | SLC13A5SLC13A2SLC13A3KDM4EMAPT | |
| SCHEMBL27383378 | 0.67 | AMY1A (0.46) | KDM4ELMNAMAPTHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102762560-A | Disubstituted heteroaryl-fused pyridines | NOVARTIS AG | 2012-10-31 | — | — | CN | disclosed |