Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28801532 | 0.75 | ALDH1A1 (0.35) | L3MBTL1ALDH1A1MAPTKMT2A | |
| SCHEMBL907751 | 0.70 | TNFSF11 (0.41) | ALDH1A1ALOX15HSD17B10 | |
| SCHEMBL11528012 | 0.69 | AR (0.44) | ARL3MBTL1ALDH1A1MAPTALOX15 | |
| SCHEMBL28026566 | 0.69 | L3MBTL1 (0.57) | ARL3MBTL1ALDH1A1MAPTALOX15 | |
| SCHEMBL27984838 | 0.68 | AR (0.36) | ARL3MBTL1ALDH1A1MAPTALOX15 | |
| SCHEMBL27984896 | 0.68 | AR (0.45) | ARL3MBTL1ALDH1A1MAPTALOX15 | |
| SCHEMBL10933998 | 0.67 | — | — | |
| SCHEMBL24260245 | 0.67 | PRKCQ (0.38) | ALDH1A1ALOX15HSD17B10 | |
| SCHEMBL11528761 | 0.66 | ALDH1A1 (0.40) | L3MBTL1ALDH1A1MAPTTP53KMT2A | |
| SCHEMBL21241200 | 0.66 | KDM4E (0.37) | ALDH1A1MAPTALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104540834-A | Novel thienopyrimidine derivatives, preparation method and therapeutic use thereof | SANOFI SA | 2015-04-22 | — | — | CN | disclosed |