Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 11/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | P4HB | P07237 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1919601 | 0.83 | MEN1 (0.61) | MEN1KMT2APOLBRAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL1476096 | 0.82 | MEN1 (0.60) | MEN1KMT2APOLBRAB9ANPC1 | |
| SCHEMBL28049599 | 0.80 | SLC6A2 (0.44) | MEN1KMT2APOLBRAB9ANPC1 | |
| Toluene SCHEMBL27486527 | 0.78 | OPRM1 (0.44) | OPRM1P4HB | |
| SCHEMBL27137776 | 0.77 | SLC6A2 (0.42) | MEN1KMT2APOLBRAB9ANPC1 | |
| SCHEMBL20493250 | 0.77 | OPRM1 (0.43) | MEN1KMT2APOLBRAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL27151922 | 0.76 | SLC6A2 (0.41) | MEN1KMT2ALMNAOPRM1OPRD1 | |
| SCHEMBL2811577 | 0.76 | LMNA (0.48) | MEN1KMT2ARAB9ANPC1LMNA | |
| SCHEMBL22085965 | 0.75 | L3MBTL1 (0.47) | OPRM1P4HBALDH1A1L3MBTL1 | |
| SCHEMBL9052620 | 0.74 | OPRM1 (0.42) | MEN1KMT2APOLBRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102791711-A | 1, 7-diazacarbazoles and their use in the treatment of cancer | HOFFMANN LA ROCHE | 2012-11-21 | — | — | CN | disclosed |