Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 14/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 5/20 | 0.43 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL232129 | 0.90 | KMO (0.52) | KMO | |
| Cyclopropane SCHEMBL28789313 | 0.84 | KMO (0.56) | KMO | |
| SCHEMBL27846612 | 0.79 | KMO (0.51) | KMOHCAR2 | |
| SCHEMBL24184895 | 0.77 | ALDH1A1 (0.40) | KMO | |
| SCHEMBL71141 | 0.76 | KMO (0.59) | KMO | |
| SCHEMBL17132794 | 0.75 | KMO (0.50) | KMO | |
| SCHEMBL15692569 | 0.74 | KMO (0.46) | KMOHCAR2 | |
| SCHEMBL294157 | 0.74 | CYP1A2 (0.49) | — | |
| Hydrochloric Acid SCHEMBL3272233 | 0.74 | KMO (0.57) | KMO | |
| Fluoride SCHEMBL21173953 | 0.74 | KMO (0.57) | KMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102985553-B | Sirtuin activator and activation determination | SIRTRIS PHARMACEUTICALS, INC. (US) | 2015-11-25 | — | — | CN | disclosed |
| CN-102985553-A | Sirtuin activators and activation assays | SIRTRIS PHARMACEUTICALS INC | 2013-03-20 | — | — | CN | disclosed |