Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 13/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20423427 | 0.87 | KDM4E (0.57) | DRD2DRD3LTA4HALDH1A1KDM4E | |
| SCHEMBL21996912 | 0.82 | S1PR5 (0.40) | HRH3MEN1KMT2A | |
| SCHEMBL26098436 | 0.80 | KDM4E (0.58) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL19611373 | 0.75 | HTR1B (0.40) | DRD2DRD3LTA4HALDH1A1KDM4E | |
| SCHEMBL2076961 | 0.75 | MAPK1 (0.37) | ALDH1A1KDM4ELMNAKMT2A | |
| SCHEMBL15435944 | 0.75 | HTR1A (0.35) | DRD2DRD3ALDH1A1KDM4EHRH3 | |
| SCHEMBL1525497 | 0.73 | CYP2J2 (0.33) | DRD2DRD3LMNAMEN1KMT2A | |
| SCHEMBL19611369 | 0.72 | ACVR1 (0.42) | DRD2DRD3ALDH1A1KDM4ELMNA | |
| SCHEMBL26101702 | 0.72 | HRH3 (0.41) | KDM4ELMNAHRH3 | |
| SCHEMBL25747712 | 0.72 | GPR4 (0.56) | DRD2DRD3LTA4HHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114702439-A | Naphthylurea-piperazine compounds and preparation method and application thereof | 河南省锐达医药科技有限公司 | 2022-07-05 | — | — | CN | disclosed |