Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP2J2 | P51589 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15435914 | 0.78 | HRH3 (0.34) | HRH3KDM4ELMNASMN1; SMN2POLB | |
| SCHEMBL15435944 | 0.77 | HTR1A (0.35) | HRH3KDM4ESMN1; SMN2 | |
| SCHEMBL26099081 | 0.74 | HRH1 (0.50) | SIGMAR1 | |
| SCHEMBL19611373 | 0.74 | HTR1B (0.40) | KDM4ELMNASMN1; SMN2RAB9APOLB | |
| SCHEMBL15435917 | 0.74 | MEN1 (0.44) | HRH3KDM4ESMN1; SMN2RAB9ASIGMAR1 | |
| SCHEMBL3657529 | 0.73 | CYP2J2 (0.32) | LMNACYP2J2 | |
| SCHEMBL15435926 | 0.73 | MEN1 (0.39) | HRH3KDM4ECYP2J2 | |
| SCHEMBL28801840 | 0.72 | DRD2 (0.47) | HRH3KDM4ELMNA | |
| SCHEMBL26098436 | 0.72 | KDM4E (0.58) | KDM4ELMNAPOLB | |
| SCHEMBL1525497 | 0.72 | CYP2J2 (0.33) | LMNACYP2J2SIGMAR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023076161-A1 | TYK2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-05-04 | — | — | WO | disclosed |