Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | RORB | Q92753 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20204270 | 0.86 | RXRA (0.36) | PTAFRKIF11NPC1RAB9AALDH1A1 | |
| SCHEMBL693026 | 0.82 | PRCP (0.34) | — | |
| SCHEMBL6912627 | 0.79 | PRCP (0.40) | NISCHALDH1A1 | |
| SCHEMBL29612349 | 0.74 | BRD4 (0.36) | PTAFRBRD4CREBBPTSHRPARP1 | |
| SCHEMBL2706486 | 0.74 | BRD4 (0.36) | PTAFRBRD4CREBBPTSHRPARP1 | |
| SCHEMBL28316529 | 0.73 | BRD4 (0.34) | BRD4CREBBPMEN1KMT2A | |
| SCHEMBL30065602 | 0.73 | PTAFR (0.39) | PTAFRBRD4CREBBPTSHRPARP1 | |
| SCHEMBL6649008 | 0.73 | BRD4 (0.36) | PTAFRBRD4CREBBPTSHRPARP1 | |
| SCHEMBL5553099 | 0.73 | PTAFR (0.39) | PTAFRBRD4CREBBPTSHRPARP1 | |
| SCHEMBL16406306 | 0.72 | PTAFR (0.39) | PTAFRBRD4CREBBPTSHRPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103086834-B | Preparation method of biaryl indene compounds | SHANGHAI RES INST CHEMICAL IND | 2015-05-27 | — | — | CN | disclosed |
| CN-103086834-A | Preparation method of biaryl indene compounds | SHANGHAI RES INST CHEMICAL IND | 2013-05-08 | — | — | CN | disclosed |