SCHEMBL2706486

SCHEMBL2706486

CC(C)(C)c1ccc(-c2cccc3c2C=CC3)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.36
CREBBP Q92793 1/20 0.36
KIF11 P52732 4/20 0.34
NPC1 O15118 4/20 0.34
RAB9A P51151 4/20 0.34
LMNA P02545 2/20 0.34
TP53 P04637 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
S1PR1 P21453 1/20 0.33
DGAT1 O75907 1/20 0.33
PARP1 P09874 1/20 0.33
NR1H4 Q96RI1 1/20 0.32
PTAFR P25105 1/20 0.32
HTR1D P28221 1/20 0.32
ADRA1A P35348 1/20 0.32
NISCH Q9Y2I1 1/20 0.32
TSHR P16473 1/20 0.31
MEN1 O00255 1/20 0.31
NR2F2 P24468 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29612349 1.00 BRD4 (0.36) BRD4CREBBPKIF11NPC1RAB9A
SCHEMBL6649008 0.98 BRD4 (0.36) BRD4CREBBPKIF11NPC1RAB9A
SCHEMBL16394708 0.86 RXRA (0.36) KIF11NPC1RAB9AALDH1A1PLA2G1B
SCHEMBL17386677 0.84 KIF11 (0.41) KIF11NPC1RAB9APTAFRALDH1A1
SCHEMBL6537096 0.82 PRCP (0.34)
SCHEMBL5348620 0.80 PRCP (0.38) ALDH1A1
SCHEMBL319986 0.79 PRCP (0.40) ALDH1A1
SCHEMBL15863965 0.78 HTR1A (0.39) NPC1RAB9ATP53SMN1; SMN2TSHR
SCHEMBL27706015 0.78 ABL1 (0.44) MEN1KMT2AALDH1A1
SCHEMBL28424140 0.78 PRCP (0.39) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3438183-B1 POLYETHYLENE AND MOLDED BODY THEREOF JAPAN POLYETHYLENE CORP (JP) 2023-11-22 EP disclosed
CN-114761449-B Catalyst 博里利斯股份公司 2023-09-08 CN disclosed
EP-3786195-B1 NOVEL TRANSITION METAL COMPOUND AND METHOD FOR PREPARING POLYPROPYLENE USING THE SAME LG CHEMICAL LTD (KR) 2023-08-02 EP disclosed
CN-112154163-B Transition metal compound and method for preparing polypropylene using the same LG化学株式会社 2022-12-27 CN disclosed
CN-114761449-A Catalyst and process for producing the same 博里利斯股份公司 2022-07-15 CN disclosed
US-11370851-B2 Transition metal compound and method for preparing polypropylene using the same LG CHEM, LTD. 2022-06-28 US disclosed
US-20210189025-A1 Novel Transition Metal Compound and Method for Preparing Polypropylene Using the Same LG CHEM, LTD. (KR) 2021-06-24 US disclosed
CN-108884282-B Polyethylene and molded article thereof 日本聚乙烯株式会社 2021-06-08 CN disclosed
EP-3786195-A1 NOVEL TRANSITION METAL COMPOUND AND METHOD FOR PREPARING POLYPROPYLENE USING SAME LG CHEM, LTD. (KR) 2021-03-03 EP disclosed
CN-112154163-A Novel transition metal compound and method for preparing polypropylene using the same LG化学株式会社 2020-12-29 CN disclosed
EP-2177544-A1 PROPYLENE POLYMER, PROCESS FOR PRODUCING THE SAME, COMPOSITION CONTAINING THE SAME, AND USE THEREOF Japan Polypropylene Corporation (JP) 2010-04-21 EP disclosed
US-7297747-B2 Polymerization process and polymer composition EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-11-20 US disclosed
US-7122498-B2 Metallocenes and catalyst compositions derived therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2006-10-17 US disclosed
US-6870016-B1 Polymerization process and polymer composition EXXONMOBIL CHEMICAL PATENTS INC. (US) 2005-03-22 US disclosed
US-20050059785-A1 Polymerization process and polymer composition HART JAMES R (US) 2005-03-17 US disclosed
US-20050054520-A1 Metallocenes and catalyst compositions derived therefrom EXXONMOBIL CHEMICAL PATENT INC. 2005-03-10 US disclosed
EP-1421090-A2 METALLOCENES AND CATALYST COMPOSITIONS DERIVED THEREFROM Exxonmobil Chemical Patents Inc. (US) 2004-05-26 EP disclosed
US-6627764-B1 Titanium, hafnium or zirconium indenyl halide complexes; coordination catalysts BASELL POLYOLEFINE GMBH (DE) 2003-09-30 US disclosed
WO-2003002583-A2 METALLOCENES AND CATALYST COMPOSITIONS DERIVED THEREFROM EXXONMOBIL CHEMICAL PATENTS INC. (US) 2003-01-09 WO disclosed
EP-1074557-A2 Transition metal complexes, ligands, catalysts, and their use in the polymerisation of olefins TARGOR GmbH (DE) 2001-02-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11370851-B2 Transition metal compound and method for preparing polypropylene using the same PPOX, PMS2, HMBS BRD4 4047/4885CREBBP 3846/4885KIF11 2541/4885
US-20210189025-A1 Novel Transition Metal Compound and Method for Preparing Polypropylene Using the Same PPOX, PMS2, HMBS BRD4 4046/4885CREBBP 3852/4885KIF11 2722/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.