Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30065602 | 1.00 | PTAFR (0.39) | PTAFRTSHRBRD4CREBBPPARP1 | |
| SCHEMBL14142022 | 0.86 | PTAFR (0.36) | PTAFRKIF11 | |
| SCHEMBL27500689 | 0.85 | KDR (0.38) | PTAFRNPC1LMNATP53RAB9A | |
| SCHEMBL16406306 | 0.83 | PTAFR (0.39) | PTAFRTSHRBRD4CREBBPPARP1 | |
| SCHEMBL3154256 | 0.82 | PDCD1 (0.38) | ALDH1A1 | |
| SCHEMBL15808761 | 0.81 | PTAFR (0.34) | PTAFRTSHRBRD4KIF11NPC1 | |
| SCHEMBL4558348 | 0.81 | PTAFR (0.37) | PTAFRTSHRBRD4CREBBPPARP1 | |
| SCHEMBL6231893 | 0.81 | PTAFR (0.37) | PTAFRTSHRBRD4CREBBPPARP1 | |
| SCHEMBL15808729 | 0.80 | PTAFR (0.39) | PTAFRTSHRBRD4KIF11NPC1 | |
| SCHEMBL27744867 | 0.78 | CD274 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4700052-A1 | HYBRID SUPPORTED METALLOCENE CATALYST AND METHOD FOR PREPARING POLYETHYLENE USING SAME | LG Chem, Ltd. (KR) | 2026-02-25 | — | — | EP | disclosed |
| US-12195563-B2 | Polyolefin-based ionomers and production thereof | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2025-01-14 | — | — | US | disclosed |
| CN-112745366-B | Silicon-based bridged metallocene compound, and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-05-24 | — | — | CN | disclosed |
| US-20240084056-A1 | Polyolefin-Based Ionomers and Production Thereof | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2024-03-14 | — | — | US | disclosed |
| EP-4271718-A1 | POLYOLEFIN-BASED IONOMERS AND PRODUCTION THEREOF | ExxonMobil Chemical Patents Inc. (US) | 2023-11-08 | — | — | EP | disclosed |
| CN-116670188-A | Polyolefin-based ionomers and preparation thereof | 埃克森美孚化学专利公司 | 2023-08-29 | — | — | CN | disclosed |
| US-20220213241-A1 | Polyolefin-Based Ionomers and Production Thereof | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2022-07-07 | — | — | US | disclosed |
| WO-2022146634-A1 | POLYOLEFIN-BASED IONOMERS AND PRODUCTION THEREOF | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2022-07-07 | — | — | WO | disclosed |
| EP-2915824-B1 | METALLOCENE LIGANDS, METALLOCENE COMPOUNDS AND METALLOCENE CATALYSTS, THEIR SYNTHESIS AND THEIR USE FOR THE POLYMERIZATION OF OLEFINS | LUMMUS NOVOLEN TECHNOLOGY GMBH (DE) | 2022-05-25 | — | — | EP | disclosed |
| CN-112745366-A | Silicon-based bridged metallocene compound and preparation method and application thereof | 中国石油化工股份有限公司 | 2021-05-04 | — | — | CN | disclosed |
| US-7199274-B2 | Preparation of substituted indenes | BASELL POLYOLEFINE GMBH (DE) | 2007-04-03 | — | — | US | disclosed |
| EP-1740622-A2 | METALLOCENE LIGANDS, METALLOCENE COMPOUNDS AND METALLOCENE CATALYSTS, THEIR SYNTHESIS AND THEIR USE FOR THE POLYMERIZATION OF OLEFINS | Novolen Technology Holdings C.V. (NL) | 2007-01-10 | — | — | EP | disclosed |
| US-20050256344-A1 | Preparation of substituted indenes | BASELL POLYOLEFINE GMBH (DE) | 2005-11-17 | — | — | US | disclosed |
| WO-2005105863-A2 | METALLOCENE LIGANDS, METALLOCENE COMPOUNDS AND METALLOCENE CATALYSTS, THEIR SYNTHESIS AND THEIR USE FOR THE POLYMERIZATION OF OLEFINS | NOVOLEN TECHNOLOGY HOLDINGS C.V. (NL) | 2005-11-10 | — | — | WO | disclosed |
| US-20050239979-A1 | Metallocene ligands, metallocene compounds and metallocene catalysts, their synthesis and their use for the polymerization of olefins | LUMMUS NOVOLEN TECHNOLOGY GMBH (DE) | 2005-10-27 | — | — | US | disclosed |
| EP-1313747-B1 | METHOD FOR PRODUCING ALKYL-BRIDGED LIGAND SYSTEMS AND TRANSITION METAL COMPOUNDS | BASELL POLYOLEFINE GMBH (DE) | 2005-04-20 | — | — | EP | disclosed |
| US-6784305-B2 | DERIVATIVES OF ZIRCONOCENE DICHLORIDE IN WHICH THE TWO SUBSTITUTED INDENYL GROUPS ARE JOINED TO ONE ANOTHER VIA A BRIDGE CAN, OWING TO THEIR CONFORMATIONAL RIGIDITY, BE USED AS CATALYSTS FOR THE STEREOSPECIFIC POLYMERIZATION OF OLEFINS | BASELL POLYOLEFINE GMBH (DE) | 2004-08-31 | — | — | US | disclosed |
| US-20030199703-A1 | Method for producing alkyl-bridged ligand systems and transition metal compounds | EQUISTAR CHEMICALS, LP | 2003-10-23 | — | — | US | disclosed |
| EP-1313747-A1 | METHOD FOR PRODUCING ALKYL-BRIDGED LIGAND SYSTEMS AND TRANSITION METAL COMPOUNDS | Basell Polypropylen GmbH (DE) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002018397-A1 | METHOD FOR PRODUCING ALKYL-BRIDGED LIGAND SYSTEMS AND TRANSITION METAL COMPOUNDS | BASELL POLYPROPYLEN GMBH (DE) | 2002-03-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256344-A1 | Preparation of substituted indenes | CYP1A2, CYP1B1, DHPS | PTAFR 2741/4885TSHR 4583/4885BRD4 2293/4885 |
| US-20030199703-A1 | Method for producing alkyl-bridged ligand systems and transition metal compounds | ABL1, ICMT, ORAI2 | PTAFR 2781/4885TSHR 1526/4885BRD4 64/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.