Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.41 |
| ▸ | HTR6 | P50406 | 9/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27885360 | 0.79 | HTR6 (0.40) | HTR6PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL27885302 | 0.79 | HTR6 (0.50) | HTR6AGTR1LMNASMN1; SMN2PSEN1 | |
| SCHEMBL27885308 | 0.76 | ALKBH5 (0.51) | HTR6AGTR1LMNASMN1; SMN2PSEN1 | |
| SCHEMBL27902312 | 0.73 | TDP1 (0.44) | MAPTALDH3A1HTR6LMNASRC | |
| SCHEMBL12093313 | 0.72 | HTR6 (0.70) | HTR6LMNAPSEN1PSEN2APH1B | |
| SCHEMBL12496512 | 0.71 | AGTR1 (0.47) | HTR6AGTR1LMNASMN1; SMN2SRC | |
| SCHEMBL12748767 | 0.71 | KMT2A (0.46) | KDM4ELMNASMN1; SMN2 | |
| SCHEMBL7192965 | 0.70 | AGTR1 (0.55) | ALDH3A1HTR6AGTR1LMNASMN1; SMN2 | |
| SCHEMBL19605706 | 0.70 | HTR6 (0.50) | HTR6AGTR1LMNASMN1; SMN2SRC | |
| SCHEMBL20762057 | 0.69 | BRD4 (0.49) | HTR6AGTR1SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102816107-B | Carbazole derivative and preparation method and use thereof | UNIV SOUTHEAST | 2015-06-03 | — | — | CN | disclosed |
| CN-102816107-A | Carbazole derivative and preparation method and use thereof | UNIV SOUTHEAST | 2012-12-12 | — | — | CN | disclosed |