SCHEMBL821811

SCHEMBL821811

C=CCN(CC=C)CNC(=O)C=C

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.50
ALDH1A1 P00352 2/20 0.50
MAPK1 P28482 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
ZDHHC20 Q5W0Z9 1/20 0.38
ZDHHC2 Q9UIJ5 1/20 0.38
TGM2 P21980 1/20 0.35
LMNA P02545 1/20 0.32
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
KDM4E B2RXH2 1/20 0.31
ALOX15 P16050 1/20 0.30
HSD17B10 Q99714 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL31470229 0.98 ALDH1A1 (0.48) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL11414150 0.82 ALDH1A1 (0.37) TSHRALDH1A1MAPK1TDP1MEN1
SCHEMBL542800 0.79 ALDH1A1 (0.46) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL3280518 0.78 ALDH1A1 (0.50) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL589167 0.77 TSHR (0.48) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL1274953 0.76 ZDHHC20 (0.50) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL3280467 0.75 ZDHHC20 (0.48) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL5965059 0.75 ZDHHC20 (0.53) TSHRALDH1A1MAPK1TDP1ZDHHC20
SCHEMBL2880291 0.74 TGFBR1 (0.32) ALDH1A1
SCHEMBL420273 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2576752-B1 THICKENER CONTAINING A CATIONIC POLYMER AND SOFTENING COMPOSITION CONTAINING SAID THICKENER, IN PARTICULAR FOR TEXTILES SPCM SA (FR) 2017-07-12 EP claimed
EP-2583762-B1 Method for temporary covering of contaminated soil EURO TEC (FR) 2014-11-19 EP claimed
US-20130101354-A1 NOVEL PROCESS FOR THE TEMPORARY COVERING OF CONTAMINATED SOILS SNF SAS (FR) 2013-04-25 US claimed
EP-2583762-A1 Novel method for temporary covering of contaminated soil SNF SAS (FR) 2013-04-24 EP claimed
US-20130090282-A1 Thickener Containing A Cationic Polymer And Softening Composition Containing Said Thickener, In Particular For Textiles S.P.C.M. SA (FR) 2013-04-11 US claimed
EP-2576752-A1 THICKENER CONTAINING A CATIONIC POLYMER AND SOFTENING COMPOSITION CONTAINING SAID THICKENER, IN PARTICULAR FOR TEXTILES S.P.C.M. SA (FR) 2013-04-10 EP claimed
WO-2011148110-A1 THICKENER CONTAINING A CATIONIC POLYMER AND SOFTENING COMPOSITION CONTAINING SAID THICKENER, IN PARTICULAR FOR TEXTILES S.P.C.M. SA (FR) 2011-12-01 WO claimed
US-6579417-B1 Paper making process for manufacturing a fibrous sheet of paper or paperboard from an aqueous suspension or a fibrous mass of pulp by flocculating said pulp with at least one water soluble cross-linked polymeric retention agent SNF S.A. (FR) 2003-06-17 US claimed
EP-1090185-A1 FLOCCULATION METHOD FOR MAKING A PAPER SHEET SNF, S.A. (FR) 2001-04-11 EP claimed
WO-2001022795-A1 FLOCCULATING (CO)POLYMER ADDITIVES AND METHODS FOR REDUCING TARE IN HARVESTED TUBER PLANTS SNF S.A. (FR) 2001-04-05 WO claimed
WO-1999061702-A1 FLOCCULATION METHOD FOR MAKING A PAPER SHEET SNF S.A. (FR) 1999-12-02 WO claimed
EP-0812618-A2 Resin fibers for treatment of oil bearing waste water and method of treating oil bearing waste water NEC CORPORATION (JP) 1997-12-17 EP claimed
EP-0089107-B1 FILTRATION OF ORGANIC SUSPENSIONS Ciba Specialty Chemicals Water Treatments Limited (GB) 1988-10-19 EP claimed
US-4405728-A Compositions for on-site mannich polymer process NALCO CHEMICAL COMPANY (US) 1983-09-20 US claimed
US-4288390-A REACTION IN AN ACIDIC MEDIUM THE DOW CHEMICAL CO. (US) 1981-09-08 US claimed
US-4265835-A USING ELECTROMAGNETIC WAVES TO QUANTITATIVELY DETECT THE PRESENCE OF CARBON-B AND THEREBY CONTROL THE MANNICH REACTION OF A CARBOXAMIDE WITH A SECONDARY AMINE AND AN ALDEHYDE THE DOW CHEMICAL COMPANY (US) 1981-05-05 US claimed
US-4139455-A Materials and processes for flotation of mineral substances ALLIED COLLOIDS LIMITED (GB) 1979-02-13 US claimed
US-4024328-A Method for alkylating aminomethylacrylamide polymers THE DOW CHEMICAL COMPANY (US) 1977-05-17 US claimed
US-20240082139-A1 USE IN AN AQUEOUS-ALCOHOLIC COMPOSITION OF POLYMERS OBTAINED BY LOW-CONCENTRATION INVERSE EMULSION POLYMERISATION WITH LOW NEUTRALISED MONOMER LEVEL SNF GROUP (FR) 2024-03-14 US disclosed
US-3959569-A Preparation of water-absorbent articles THE DOW CHEMICAL COMPANY (US) 1976-05-25 US disclosed