Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 2/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 8/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23805008 | 0.84 | P2RX7 (0.48) | P2RX7MCL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL18588937 | 0.77 | MCL1 (0.38) | CFDGRIN1GRIN2ANOTUMGRIA2 | |
| SCHEMBL26051685 | 0.77 | ALDH1A1 (0.36) | CFDGRIN1GRIN2AP2RX7ADORA2A | |
| SCHEMBL28803282 | 0.76 | P2RX7 (0.51) | CFDP2RX7ALDH1A1SMN1; SMN2 | |
| SCHEMBL25370780 | 0.76 | P2RX7 (0.35) | CFDGRIN1GRIN2AP2RX7ALDH1A1 | |
| SCHEMBL30580183 | 0.76 | P2RX7 (0.35) | CFDGRIN1GRIN2AP2RX7ALDH1A1 | |
| SCHEMBL1344741 | 0.74 | AKR1B1 (0.44) | GRIN1GRIN2ANOTUM | |
| SCHEMBL12648422 | 0.73 | GABRA1 (0.40) | GRIN1GRIN2ANOTUMGRIA2ALDH1A1 | |
| SCHEMBL15018243 | 0.73 | PTGDR2 (0.41) | CFDGRIN1GRIN2ANOTUMGRIA2 | |
| SCHEMBL15018240 | 0.73 | NOTUM (0.36) | GRIN1GRIN2ANOTUMGRIA2MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109121414-B | Benzopyrazole compounds and analogs thereof | 拜奥克里斯特制药公司 | 2022-07-05 | — | — | CN | disclosed |