Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CFD | P00746 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 9/20 | 0.34 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28803365 | 0.77 | CFD (0.39) | ALDH1A1CFDP2RX7GRIN1GRIN2A | |
| SCHEMBL26051489 | 0.75 | SMN1; SMN2 (0.49) | SMN1; SMN2NAMPT | |
| SCHEMBL30580183 | 0.74 | P2RX7 (0.35) | ALDH1A1CFDP2RX7GRIN1GRIN2A | |
| SCHEMBL25370780 | 0.74 | P2RX7 (0.35) | ALDH1A1CFDP2RX7GRIN1GRIN2A | |
| SCHEMBL26051687 | 0.71 | EPHX2 (0.36) | ALDH1A1CFDP2RX7NPC1RAB9A | |
| SCHEMBL26050994 | 0.70 | P2RX7 (0.35) | CFDP2RX7GRIN1GRIN2A | |
| SCHEMBL26051496 | 0.70 | MLYCD (0.52) | NPC1RAB9AKDM4ENPSR1MEN1 | |
| SCHEMBL26051512 | 0.70 | MTOR (0.55) | NPC1MEN1KMT2A | |
| SCHEMBL18588937 | 0.68 | MCL1 (0.38) | ALDH1A1CFDKDM4EGRIN1GRIN2A | |
| SCHEMBL26051713 | 0.67 | RORC (0.39) | ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023158584-A1 | NEW BICYCLOPENTANE DERIVATIVES | ICAGEN, LLC (US) | 2023-08-24 | — | — | WO | disclosed |