SCHEMBL28804273

SCHEMBL28804273

C=C(NC(=O)Nc1ccc(S(N)(=O)=O)cc1)C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.67
CA2 P00918 17/20 0.64
CA12 O43570 16/20 0.64
CA1 P00915 16/20 0.64
CA9 Q16790 16/20 0.64
CA4 P22748 1/20 0.58
CA7 P43166 1/20 0.58
PTPN7 P35236 1/20 0.58
MEN1 O00255 1/20 0.58
MAPT P10636 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28804298 0.86 TIMP3 (0.51) KMT2ACA2CA12CA1CA9
SCHEMBL23086242 0.82 CA2 (0.87) KMT2ACA2CA12CA1CA9
SCHEMBL28499329 0.81 KMT2A (1.00) KMT2ACA2CA12CA1CA9
SCHEMBL5705825 0.79 KMT2A (0.63) KMT2ACA2CA12CA1CA9
SCHEMBL7094785 0.79 CA2 (0.62) KMT2ACA2CA12CA1CA9
SCHEMBL671546 0.78 CA2 (1.00) KMT2ACA2CA12CA1CA9
SCHEMBL28804176 0.78 MAOA (0.58) KMT2ACA2CA12CA1CA9
SCHEMBL28946873 0.77 EPHX2 (0.51) KMT2ACA2CA12CA9MEN1
SCHEMBL28946861 0.77 ALDH1A1 (0.51) PTPN7MAPT
SCHEMBL15913775 0.76 CA2 (0.61) KMT2ACA2CA12CA1CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109791361-B Positive lithographic printing plate precursor, method for producing same, and method for producing lithographic printing plate 富士胶片株式会社 2022-06-03 CN disclosed