Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL9 | O00512 | 1/20 | 0.51 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12466759 | 0.77 | PTGDR2 (0.52) | LMNAPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL508765 | 0.75 | PTGDR2 (0.51) | PTGDR2 | |
| SCHEMBL28384556 | 0.74 | PTGDR2 (0.40) | LMNAHTTPDE4APDE4BPDE4C | |
| SCHEMBL28384554 | 0.74 | PTGDR2 (0.44) | PDE4APDE4BPDE4CPDE4DPTGDR2 | |
| SCHEMBL31395703 | 0.71 | PTGDR2 (0.43) | LMNAKMT2AMEN1PTGDR2ALDH1A1 | |
| SCHEMBL4219270 | 0.70 | TGM2 (0.45) | LMNASMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL14979169 | 0.69 | ALDH1A1 (0.59) | LMNAPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL133257 | 0.69 | BCL9 (1.00) | BCL9CTNNB1LMNAHTTSMN1; SMN2 | |
| SCHEMBL27903175 | 0.69 | LMNA (0.51) | LMNAHTTPDE4APDE4BPDE4C | |
| SCHEMBL26111924 | 0.68 | BCL9 (0.97) | BCL9CTNNB1LMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103339125-A | Pyrazole compounds as CRTH2 antagonists | BOEHRINGER INGELHEIM INT | 2013-10-02 | — | — | CN | disclosed |