SCHEMBL28808583

SCHEMBL28808583

CCCO[Si](OCCC)(OCCCOC)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
MAPK1 P28482 2/20 0.35
KCNH3 Q9ULD8 1/20 0.35
ALDH1A1 P00352 2/20 0.34
LTA4H P09960 2/20 0.33
POLB P06746 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
LMNA P02545 2/20 0.33
KDM4E B2RXH2 1/20 0.32
CA2 P00918 1/20 0.32
ADORA2A P29274 1/20 0.32
ADORA2B P29275 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8678984 0.93 MAPK1 (0.39) MEN1KMT2AMAPK1KCNH3ALDH1A1
SCHEMBL9228586 0.87 LTA4H (0.44) MEN1KMT2AMAPK1ALDH1A1LTA4H
SCHEMBL105659 0.87 LMNA (0.39) MEN1KMT2AALDH1A1LTA4HLMNA
SCHEMBL431649 0.83 LTA4H (0.47) MAPK1ALDH1A1LTA4HTDP1
SCHEMBL61765 0.83 HTR1B (0.34) MEN1KMT2ALTA4HLMNA
SCHEMBL28045151 0.83 LTA4H (0.33) MEN1KMT2AALDH1A1LTA4HLMNA
SCHEMBL19809137 0.83 LMNA (0.36) MEN1KMT2AMAPK1ALDH1A1LTA4H
SCHEMBL7863713 0.82 LMNA (0.36) MEN1KMT2AALDH1A1LTA4HLMNA
SCHEMBL669703 0.82 LMNA (0.36) MEN1KMT2AALDH1A1LTA4HPOLB
SCHEMBL3294910 0.82 LMNA (0.36) MEN1KMT2AALDH1A1LTA4HPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101641767-B Silicon dielectric treating agent for use after etching, process for producing semiconductor device, and semiconductor device FUJITSU LTD 2013-10-30 CN disclosed